Protein Alignment Smvt and Slc5a12

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001102058.1
• Gene: Slc5a12 / 362188
• RGDID: 1311652
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 194/571 - (33%)
• Similarity: 297/571 - (52%)
• Gaps: 55/571 - (9%)

  Fly    24 FNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTI 88
            |.|.||.|||.:..||:.|||:|....:.:.|:.|:|:||::|...|:|:||.||.:||::::..
  Rat     6 FEAWDYVVFAALFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFAPVALSLTASFMSAVTVLGT 70

  Fly    89 PAEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQTFIFILTM 153
            |||:|.:|.:::..::....||...:.|.:||||.:.||:.||||::||.:.||...|.|:||..
  Rat    71 PAEVYRFGASFLIFLISYAFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYILQT 135

  Fly   154 FFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVLVG 218
            .....:.::.|:||..||||||:.........:|.||...||:|||||||..|..:|:...:.|.
  Rat   136 ILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVL 200

  Fly   219 VLGAHRVGGFFEVLRIAGEGGRLDI-NYNFDLTTRSTIWNIFTSATMMWTGYVGLNQSCVQRIVS 282
            :.|::.||||..||..|..|.|||| :::.|...|.|.|.|....|..|.|..|:|||.:||.:|
  Rat   201 IQGSNHVGGFDNVLEQARNGSRLDIVDFDVDPLRRHTFWTIAVGGTFTWLGIYGVNQSTIQRCIS 265

  Fly   283 LPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTVGNL 347
            ..:..||:.:|.....|..:|:....|.|:::|:.:.||||..||.:...|:::||||.:....:
  Rat   266 CKTEKHAKLALYFNLLGLWIIVVCAVFCGLIMYAYYKDCDPWTSGAILAPDQLMPYFVMEIFATM 330

  Fly   348 WGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIK---PHIRHTEHRANVIMKLFVFFTGIYCI 409
            .|:||:|::|.||..|||::||||:|..|.:.|::|   ||:..|  .:..|.|......||.|.
  Rat   331 PGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDT--LSTWISKGLCLLFGIICT 393

  Fly   410 LGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVGVLASIACMATIVILSWG 474
            ...::.....|::|...||.||..|...|:|.||::.|..:.:.||.|:|..|.....:.|   |
  Rat   394 SMAVLASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTGITLSFWVGI---G 455

  Fly   475 RNHYDTLPTSTSACPASLNGTIKDISTASPLFLGSTTEA------PVGEKEFSILDLSFNWYTVT 533
            ...|....:.|...|.|....::...|        ||||      ||         |:..||:::
  Rat   456 AFVYPAPDSKTLPLPLSTEFCVQQNKT--------TTEAYQLSSRPV---------LADTWYSLS 503

  Fly   534 ---------------GFVITWLIGIPLSYILKSGPDYKPNPKLLSPVVQPF 569
                           |.:|::|.|      .:.|.|.  :|.|:.||...|
  Rat   504 YLYFSAVGCLGCIAAGIIISFLTG------RQRGKDV--DPLLIRPVCNLF 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	185/545 (34%)
Slc5a12	NP_001102058.1	SLC5sbd_SMCT2	3..527	CDD:212089	186/542 (34%)