Protein Alignment Smvt and Gm5134

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: XP_006513854.1
• Gene: Gm5134 / 333669
• MGIID: 3646667
• Length: 695
• Species: Mus musculus
• Alignment Length: 580
• Identity: 119/580 - (20%)
• Similarity: 226/580 - (38%)
• Gaps: 99/580 - (17%)

  Fly    25 NATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIP 89
            :.||..|....|.:...:|:: ...:....|.:::.:.|:.:....:.||:.:|.:.:...|.:.
Mouse    23 STTDTLVMTFYLLLVVCVGLW-ALLSHSRGTVKDFFLAGQNLAWWLMGISIYSSNIGSGHYMALA 86

  Fly    90 AEMYAYGI-----NWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRF-CRKVRVLQTFI 148
            ....|.||     .|  |.:.|:.   ||.::.:|::....:....|||:.|| ..::::..|||
Mouse    87 GIGAASGIAVGALEW--NSIFMLF---LLGWIFVPIYSKAEVVTLPEYLKKRFGSLRIQLFFTFI 146

  Fly   149 FILT-MFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVA 212
            |::. :|..:.:.|...::....|...:::.....|.:|...||:.||:..|.:.:.:||.||:.
Mouse   147 FLIVYIFSRISMEIGFGAMFLKMVWDTDIYQTMLTVLTIIGMYTITGGLATVAYVESLQAGIMIL 211

  Fly   213 SVVLVGVLGAHRVGG-------FFEVLRIAGEGGRLDINYNFDLTTRSTIWNIF---TSATMMWT 267
            ...|:.....:.|||       :.|.:....:.|.........| .|...::||   .|..:.|.
Mouse   212 GSALLMGYAFYEVGGYPKLVSKYMEAIPSKTQQGNWTAQPECYL-PRQDAFHIFRSCVSGDIPWP 275

  Fly   268 G-----------YVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDC 321
            |           |...:|..|||.::..|..|.....:|.|:..:|.||.....|::  ||....
Mouse   276 GLILGATTVSLFYGCADQVSVQRFLAGKSRLHMEGGCLLCGYLKLLPMFLMVMPGMI--SRILYP 338

  Fly   322 DPIQSGHVSKVDKM-----------VPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGG 375
            |.:.....|:..|.           .|..|...:.:  |:.|..:|.|.::.:|:|::..||...
Mouse   339 DQVACVVPSECQKFCGRGTGCSALAYPVLVLGVMPH--GLQGFMLSTVCASLMSSLTSIFNSSSA 401

  Fly   376 VV---YFDYIKPHIRHTEHRANVIMKLFVFFTGIYCILGGMVIENF-NSIL----QVIYSIGGMS 432
            :.   .:.:|:|  ..||....:..:.||.......|:...:||.. |.||    ||:.|   ..
Mouse   402 LFTLNIYTWIRP--TATEKELMIAGRFFVIILLAVTIVWIPIIEMAPNEILFEYMQVLKS---CL 461

  Fly   433 FGSTCGVFMLGMLVPKSHGRAALVGVL--ASIACMATIVILSWGRNHYDTLPTSTSACPASLNGT 495
            ..|...||:|.:...:.:.:.|..|::  .:|.....:....:|
Mouse   462 TPSMTAVFLLAVFCKRVNEQGAFWGLIVGTTIGVFRLLAEFFYG--------------------- 505

  Fly   496 IKDISTASPLFLGSTTEAPVGEKEFSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPDY 555
                    |:..|...:.|:     .|..|.:.::....|::|.||.:.:|...:..||:
Mouse   506 --------PVTCGRDRQCPI-----FICGLHYLYFGFCLFLVTILIILAISLATEPIPDH 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	117/569 (21%)
Gm5134	XP_006513854.1	SLC5-6-like_sbd	26..695	CDD:444915	118/577 (20%)