Protein Alignment Smvt and Slc5a6

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_808538.1
• Gene: Slc5a6 / 330064
• MGIID: 2660847
• Length: 634
• Species: Mus musculus
• Alignment Length: 619
• Identity: 196/619 - (31%)
• Similarity: 314/619 - (50%)
• Gaps: 57/619 - (9%)

  Fly    10 LATAATVVP--------DSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRM 66
            ::.|:|..|        .:...|:..||.||.|:|.:|..||:|......|..|..|.||..::|
Mouse     1 MSVASTAAPFHTTSGSSGAISTFSVVDYVVFGLLLVLSLVIGLYHACRGWGHHTVGELLMADRKM 65

  Fly    67 KTIPIAISLVASQLSAISIMTIPAEMYAYGINWVFNVVC---MVLVVPLLNYLVIPVFYNNNITN 128
            ..:|:|:||:|:..||::|:..|||::.:|..:.| :.|   :.|::|.  ::.|||||..::|:
Mouse    66 GCLPVALSLLATFQSAVAILGAPAEIFRFGTQYWF-LGCSYFLGLLIPA--HIFIPVFYRLHLTS 127

  Fly   129 CYEYLEMRFCRKVRVLQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMF 193
            .|||||:||.:.||:..|..||..|...:.:.::.||||...||||::.|....:..:|..||..
Mouse   128 AYEYLELRFNKAVRICGTVTFIFQMVIYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTAL 192

  Fly   194 GGIKAVVWTDVIQAAIMVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLD-INYNFDLTTRSTIWN 257
            ||:|||:||||.|..:|....::|.::||.||||...|..:..:.|.:. ||.:.|...|.|.|.
Mouse   193 GGLKAVIWTDVFQTLVMFLGQLVVIIVGAARVGGLGHVWNVTSQHGLISGINLDPDPFVRHTFWT 257

  Fly   258 IFTSATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFI----LIMFFNCFTGIVIYSRF 318
            :......|.....|:||:.|||.:|    .|:.|:.||..:...    :.:..:|..|:|:::.:
Mouse   258 LAFGGVFMMLSLYGVNQAQVQRYLS----SHSERAAVLSCYAVFPCQQVALCMSCLIGLVMFAYY 318

  Fly   319 HDCDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIK 383
            :..........:..|::|.|||.|.:.::.|:||:|::|:||.:|||:|::.|||..|...|.|:
Mouse   319 NMYSMSPELKQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQ 383

  Fly   384 PHI-RHTEHRANVIMKLFVFFTGIYCILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVP 447
            |.. :.||.||.::.:...|..|:.|:....:..:..|:||...||.||..|...|:|.||:..|
Mouse   384 PWFPQLTETRAIMLSRGLAFAYGLVCLGMAYISSHLGSVLQAALSIFGMVGGPLLGLFCLGLFFP 448

  Fly   448 KSHGRAALVGVLASIACMATIVILSWGRNHYDTLPTSTSACPASLNG---------TIKDISTAS 503
            .::...|:||:|..:.....|.|.|      .....|::..|..|||         |:..::|..
Mouse   449 CANPLGAIVGLLTGLTMAFWIGIGS------IVSRMSSAVAPPPLNGSSSFLPANVTVAAVTTVM 507

  Fly   504 PLFLGSTTEAPVGEKEFSILDLSFNWYT--------VTGFVITWLIGIPLSYILKSGPDYKPNPK 560
            |    ||...|.|.:.|  ..||:.||:        |.|.:::.|.|......|..|..|...||
Mouse   508 P----STLSKPTGLQHF--YSLSYLWYSAHNSTTVIVVGLIVSLLTGGMRGRSLNPGTIYPVLPK 566

  Fly   561 LLS--PV-VQPFVHYKLTPSDEPHQLNLEKPEKV 591
            ||:  |: .|..:.::....|.|...|| .|||:
Mouse   567 LLALLPLSCQKRLCWRSHSQDIPVIPNL-FPEKM 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	176/546 (32%)
Slc5a6	NP_808538.1	SLC5-6-like_sbd	23..548	CDD:444915	176/543 (32%)