DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smvt and CG31262

DIOPT Version :9

Sequence 1:	NP_651891.2	Gene:	Smvt / 43744	FlyBaseID:	FBgn0039873	Length:	591	Species:	Drosophila melanogaster
Sequence 2:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster

Alignment Length:	576	Identity:	180/576 - (31%)
Similarity:	296/576 - (51%)	Gaps:	51/576 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FNATDYGVFALVLSISAAIGVYFGFFAK-----------------GEDTTEEYLMGGKRMKTIPI 71
            |...||.|...:..:|...|:|||...|                 |.:..:|||||.:.||.||:
  Fly     6 FGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPV 70

  Fly    72 AISLVASQLSAISIMTIPAEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMR 136
            :|:|    ....||:..|:|:|.||..:...:|.::|.....:|:.:||:....|.:.||||.:|
  Fly    71 SITL----YRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLR 131

  Fly   137 FCRKVRVLQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVW 201
            |...:|...:|:::..:...||..:::|:|:.:||:|.|.|||..|:...||.||..||:||||.
  Fly   132 FNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMGGLKAVVH 196

  Fly   202 TDVIQAAIMVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLDI-NYNFDLTTRSTIWNIFTSATMM 265
            |||.|.|:|..|:|.|..|..:...|...|...|.:||||.: |.|.....|.|:|::.......
  Fly   197 TDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSVLIGGFSF 261

  Fly   266 WTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQSGHVS 330
            ||......|..|||.:|||||..:|::..:|..|..:.:...||.|::::|::.||||..:|.:.
  Fly   262 WTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCDPRSAGMIL 326

  Fly   331 KVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKPHIR--HTEHRA 393
            ..|:::|.||..:||:::||||:||:.:|.|.||:||:..|::..|...|.::...:  .:|.::
  Fly   327 NDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQS 391

  Fly   394 NVIMKLFVFFTGIYCILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVGV 458
            .:::|..:.|.||...|...::::...||.|..||..::.|::.|||.||||.|.::.....||.
  Fly   392 TILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVGG 456

  Fly   459 LASIACMATI-----VILSWGRNHYDTLPTSTSACPASLNGTIKDISTASPLFLGSTT--EAPVG 516
            |:|:.....|     :..:.|:.....||.|...|                  :|:.|  |.|..
  Fly   457 LSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKEC------------------VGNVTLPEDPWV 503

  Fly   517 EKE--FSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPDYKPNPKLLSPVVQPFV 570
            :::  |.:..||::|.:..|.|...::|..:|.|.|.......:.:|:|||:..|:
  Fly   504 DQDQVFPLYRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISPVIHRFL 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	172/549 (31%)
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	168/534 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448228
Domainoid	1	1.000	97	1.000	Domainoid score	I370
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900