Protein Alignment Smvt and Slc5a10

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001100477.1
• Gene: Slc5a10 / 303205
• RGDID: 1305232
• Length: 596
• Species: Rattus norvegicus
• Alignment Length: 569
• Identity: 132/569 - (23%)
• Similarity: 242/569 - (42%)
• Gaps: 83/569 - (14%)

  Fly    18 PDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSA 82
            |.||  .:.:|..|.:|..:::.|:||:....| .::|...|.:.|:.|...||..||.||...:
  Rat    12 PGSQ--LSTSDIIVISLYFALNVAVGVWTACRA-NKNTVSGYFLAGRDMAWWPIGASLFASSEGS 73

  Fly    83 ISIMTIPAEMYAYGI---NWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRF-CRKVRV 143
            ...:.:.....|.|:   .:.:|...::|.   |.::.:|::.::.|....||::.|| .:::|:
  Rat    74 GLFIGLAGSGAAGGLAVAGFEWNATYVLLA---LAWVFVPIYVSSEIVTLPEYIQKRFGGQRIRM 135

  Fly   144 -LQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQA 207
             |.....:|::|..:.|.::..:|......|:|.:|...:..:|...||:.||:..|::||.:|.
  Rat   136 YLSVLSLLLSVFTKISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQT 200

  Fly   208 AIMVASVVLVGVLGAHRVGGFFEVLRIAGEGG--------------RLDINYNF-DLTTRSTIWN 257
            ||||...|::.|...:::|| :|.|..|....              |.|..:.| |.:|....|.
  Rat   201 AIMVVGAVILAVKAFNQIGG-YEQLEAAYAQATPSRTIPNTTCHLPRADAMHMFRDPSTGDLPWT 264

  Fly   258 IFT-SATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGF------------GFILIMFFNCF 309
            ..| ..|:|.|.|...:|..|||.:|..:|.||:...:|..:            |.|..:.|...
  Rat   265 GMTFGLTIMATWYWCTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMPGMISRVLFPDD 329

  Fly   310 TGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLG 374
            .|.|:.|   :|.......:...:...|..|.:.:.  .|:.|:.|:.:.:|.||:|::..||..
  Rat   330 VGCVVPS---ECLRACGAEIGCSNIAYPKLVMELMP--IGLRGLMIAVMMAALLSSLTSIFNSSS 389

  Fly   375 GVVYFD---YIKPHIRHTEHRANVIMKLFVFFTGIYCILGGM------VIENFNSILQVIY--SI 428
            .:...|   ..:|.....|        |.:....:..:|.|:      |::..||....||  |:
  Rat   390 TLFTMDIWRQFRPGAGERE--------LLLVGRLVIVVLVGVSVAWIPVLQGSNSGQLFIYMQSV 446

  Fly   429 GGMSFGSTCGVFMLGMLVPKSHGRAALVGVLASIACMATIVILS--WGRNHYDTLPTSTSACPAS 491
            ..........:|:||:...:::.:.|..|::|.:...|..::|.  :...|...:.|.    |..
  Rat   447 TSSLAPPVTAIFLLGIFWRRANEQGAFWGLMAGLLVGALRLVLEFLYPEPHCGQIDTR----PFP 507

  Fly   492 LNGTIKDISTASPLFL--------GSTTEAPVGEKEFSILDLSFNWYTV 532
            | |:|..:..|..||.        ||....|..:::..    :..|:|:
  Rat   508 L-GSIHYLHFAIALFFLTCAVMAAGSLLSPPPQQRQIE----NLTWWTL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	129/560 (23%)
Slc5a10	NP_001100477.1	SLC5-6-like_sbd	17..596	CDD:444915	129/562 (23%)