Protein Alignment Smvt and Slc5a4

DIOPT Version :9

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001099853.1
• Gene: Slc5a4 / 294341
• RGDID: 1306923
• Length: 671
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 129/656 - (19%)
• Similarity: 256/656 - (39%)
• Gaps: 144/656 - (21%)

  Fly     1 MSSLLNATVLATAATVVPDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKR 65
            |:|..:.:....::.:...|..:.|..|..|..:...:..|:||: ........|...:.:.|:.
  Rat    12 MASTASVSTSTGSSELSSLSDNINNPADISVIVIYFVVVMAVGVW-AMVKTNRSTVGGFFLAGRS 75

  Fly    66 MKTIPIAISLVASQLSAISIMTIPAEMYAYGIN-WVFNVVCMVLVVPLLNYLVIPVFYNNNITNC 129
            |...|:..||.||.:.:...:.:.....|.||. ..|......|:: :|.:..:|::....:...
  Rat    76 MTWWPMGASLFASNIGSGHFVGLAGTGAATGIAVTAFESHSFALLL-VLGWFFVPIYIKAGVMTM 139

  Fly   130 YEYLEMRFCRKVRVLQTFIFILTMFFMLPIF----IFLPSLAFAQVTGFNVHLINTVVCSICVFY 190
            .|||..||..|  .||.::.:|::|..:.:.    ||..::......|.:::|...::.:|...:
  Rat   140 PEYLRKRFGGK--RLQIYLSVLSLFICVILTISADIFSGAIFIKLALGLDLYLAIFILLAITAVF 202

  Fly   191 TMFGGIKAVVWTDVIQAAIMVASVVLVGVLGAHRVGG-------FFEVLRIAGEGGRLDIN---Y 245
            |:.||:.:|::||.:||.||:....::.:.....|||       :...:....||..|.|:   |
  Rat   203 TITGGLASVIYTDTLQAIIMLVGSFILMIYAFVEVGGYESFTEKYMNAIPSVVEGDNLTISPKCY 267

  Fly   246 NFDLTTRSTIWNIFTSA----------------TMMWTGYVGLNQSCVQRIVSLPSLGHARRSLV 294
                |.:...::||..|                |.:|  |..:||..|||.:...::.|.:.:.:
  Rat   268 ----TPQPDSFHIFRDAVTGDIPWPGTAFGMPITALW--YWCINQVIVQRCLCGKNMSHVKAACI 326

  Fly   295 LFGFGFILIMFFNCFTGI---VIYSRFHDC-DPIQSGHVSKVD-------------KMVPYFVQD 342
            :.|:..:|.:||....|:   ::|:....| .|.:......||             |::|
  Rat   327 VCGYLKLLPIFFMVMPGMISRILYTDMVACVVPSECVKQCGVDVGCTNYAYPMLVLKLMP----- 386

  Fly   343 TVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFD-YIKPHIRHTEHRANVIMKLFVFFTGI 406
                 .|:.|:.:|.:.::.:|:|::..||...:...| |.|...:.:|....:..:|||....:
  Rat   387 -----MGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDLYTKIRKKASERELLIAGRLFVSVLIV 446

  Fly   407 YCILGGMVIENFNSILQVIYSIGGMSFGST-----------CGVFMLGMLVPKSHGRAALVGVLA 460
            ..||...::|         .|.||.....|           ..||::.:...:.:.:.|..|::.
  Rat   447 TSILWVPIVE---------VSQGGQLIHYTEAISSYLGPPIAAVFLVAIFCKRVNEQGAFWGLMV 502

  Fly   461 S--IACMATIVILSWGRNHYDTLPTSTSACPASLNGTIKDISTASPLFLGSTTEAPVGEKEFSIL 523
            .  :..:..|...|:|....    .:.|:||..:.|
  Rat   503 GLVLGLIRMIAEFSYGTGSC----LAPSSCPKVICG----------------------------- 534

  Fly   524 DLSFNWYTVTGFVITWLIGIPLSYILKSGPDYKPNPKLLSPVVQPFVH-YKLTPS---DEPHQLN 584
             :.:.:|.:..|.::.|:.:.:||:.|..||               || |:|..|   .|..:::
  Rat   535 -VHYLYYAIILFFVSILVILGVSYLTKPIPD---------------VHLYRLCWSLRNSEEERID 583

  Fly   585 LEKPEK 590
            |:..::
  Rat   584 LDAEDR 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	114/582 (20%)
Slc5a4	NP_001099853.1	SLC5-6-like_sbd	38..671	CDD:294310	125/630 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340187
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740