Protein Alignment Smvt and Slc5a12

DIOPT Version :9

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001003915.1
• Gene: Slc5a12 / 241612
• MGIID: 2138890
• Length: 623
• Species: Mus musculus
• Alignment Length: 582
• Identity: 197/582 - (33%)
• Similarity: 300/582 - (51%)
• Gaps: 73/582 - (12%)

  Fly    24 FNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTI 88
            |.|.||.|||.:..||:.|||:|....:.:.|:.|:|:||::|...|:|:||.||.:||::::..
Mouse     6 FEAWDYVVFAGLFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFGPVALSLTASFMSAVTVLGT 70

  Fly    89 PAEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQTFIFILTM 153
            |||:|.:|.::...::..|.||...:.|.:||||.:.||:.||||::||.:.||...|.|:|:..
Mouse    71 PAEVYRFGASFFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYIVQT 135

  Fly   154 FFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVLVG 218
            .....:.::.|:||..||||||:.........:|.||...||:|||||||..|..:|:...:.|.
Mouse   136 ILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVL 200

  Fly   219 VLGAHRVGGFFEVLRIAGEGGRLDI-NYNFDLTTRSTIWNIFTSATMMWTGYVGLNQSCVQRIVS 282
            :.|::.||||..||..||.|.||.| :::.|...|.|.|.|....|..|.|..|:|||.:||.:|
Mouse   201 IQGSNHVGGFNNVLEKAGNGSRLHIVDFDVDPLRRHTFWTITIGGTFTWLGVYGVNQSTIQRCIS 265

  Fly   283 LPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTVGNL 347
            ..:..||:.:|.....|..:|:....|:|:::||.|.||||..||.:|..|:::||||.:....:
Mouse   266 CKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVISAPDQLMPYFVMEIFATM 330

  Fly   348 WGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIK---PHIRHTEHRANVIMKLFVFFTGIYCI 409
            .|:||:|::|.||..|||::||||:|..|.:.|::|   ||:  ::..:..|.|......||.|.
Mouse   331 PGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHL--SDKLSTWISKGLCILFGIMCT 393

  Fly   410 LGGMVIENFNSILQV--IYS----IGG---MSFGSTC-GVFMLGMLVPKSHGRAALVGVLASIAC 464
            ...:|.....|::|.  |.|    |.|   .:..|.| ||.:..:::      .||.|:|..|..
Mouse   394 SMAVVASLMGSVVQAPGIVSQERAITGSFQRNLASVCYGVSIWKLIM------GALGGLLTGITL 452

  Fly   465 MATIVILSWGRNHYDT-------LPTSTSACPASLNGTIKDISTASPLFLGSTTEAPVGEKEFSI 522
            ...:.|   |...|..       ||.||..| ..||.|    :|.:|    ..:..||
Mouse   453 SFWVAI---GSFIYPAPESKTLPLPLSTEHC-VELNIT----TTVAP----QISSRPV------- 498

  Fly   523 LDLSFNWYTVT---------------GFVITWLIGIPLSYILKSGPDYKPNPKLLSPVVQPF 569
              |:..||:::               |.:|::|.|      .:.|.|.  :|.|:.||...|
Mouse   499 --LADTWYSLSYLYFSAVGCLGCIAAGIIISFLTG------KQRGKDI--DPLLIRPVCNLF 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	188/556 (34%)
Slc5a12	NP_001003915.1	SLC5-6-like_sbd	3..531	CDD:294310	189/553 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836508
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.840