Protein Alignment Smvt and Slc5a11

DIOPT Version :9

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_666310.1
• Gene: Slc5a11 / 233836
• MGIID: 1919316
• Length: 673
• Species: Mus musculus
• Alignment Length: 692
• Identity: 157/692 - (22%)
• Similarity: 270/692 - (39%)
• Gaps: 178/692 - (25%)

  Fly    13 AATVVP-----DSQFVF-----NATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMK 67
            :||:.|     ||...|     ...|..|..|......|:|::.....| .||.:.|.:.|..|.
Mouse     3 SATISPQPPQSDSLEAFPQKSMEPADIAVLVLYFLFVLAVGLWSTVRTK-RDTVKGYFLAGGDMV 66

  Fly    68 TIPIAISLVASQLS-------AISIMTIPAEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNN 125
            ..|:..||.||.:.       |.|...:...:.||.:|.:|:|:       :|.::.:|::....
Mouse    67 WWPVGASLFASNVGSGHFIGLAGSGAAVGISVAAYELNGLFSVL-------MLAWVFLPIYIAGQ 124

  Fly   126 ITNCYEYLEMRF-----CRKVRVLQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCS 185
            :|...|||..||     ...:.||..||:|.|   .:.:.::..::...|....:::|....:.:
Mouse   125 VTTMPEYLRRRFGGNRISITLAVLYLFIYIFT---KISVDMYAGAIFIQQSLHLDLYLAIVGLLA 186

  Fly   186 ICVFYTMFGGIKAVVWTDVIQAAIM-VASVVLVGVLGAHRVGGFFEVLRIAGEGGRLDINYNFDL 249
            |...||:.||:.||::||.:|..|| :.:.:|:|...| .|||.        ||  |...|...|
Mouse   187 ITALYTVAGGLAAVIYTDALQTVIMLIGAFILMGYSFA-AVGGM--------EG--LKDQYFLAL 240

  Fly   250 TT-----------RSTIWNIF---TSATMMWTG-----------YVGLNQSCVQRIVSLPSLGHA 289
            .:           |...::||   .::.:.|.|           |...:|..|||.::..:|.||
Mouse   241 ASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGILFGMSIPSLWYWCTDQVIVQRSLAAKNLSHA 305

  Fly   290 RRSLVLFGFGFILIMFFNCFTGIVIYSRFHD---------CDPIQSGHVSKVDKMVPYFVQDTVG 345
            :...::..:..:|.:|...|.|:|....|.|         |..:.|......|...|..|.:.:.
Mouse   306 KGGSLMAAYLKVLPLFLMVFPGMVSRVLFPDQVACAHPDICQRVCSNPSGCSDIAYPKLVLELLP 370

  Fly   346 NLWGMPGVFISCVFSAALSTLSASINSLGGVVYFD---YIKPHIRHTEHRANVIMKLFVFFTGIY 407
            .  |:.|:.::.:.:|.:|:|::..||...:...|   :|:|  |.:|....::.::|||...:.
Mouse   371 T--GLRGLMMAVMVAALMSSLTSIFNSASTIFTMDLWNHIRP--RASERELMIVGRIFVFALVLV 431

  Fly   408 CIL---------GGMV---IENFNSILQ----VIYSIG---------GMSFGSTCGVFMLGML-- 445
            .||         ||.:   |::.:|.||    :::.:|         |...|...|: :||::
Mouse   432 SILWIPIVQASQGGQLFIYIQSISSYLQPPVAMVFIMGCFWKRTNEKGAFSGLILGL-LLGLVRL 495

  Fly   446 ----------VPKSHGRAALV--------GVLASIACMATIVILSWGRN---------------- 476
                      ..:...|.|:|        .::.|...:.|:|.:||...
Mouse   496 ILDFVYAQPRCDQPDDRPAVVKDVHYLYFSMILSFTTLITVVTVSWFTETPSKEMVSRLTWFTRH 560

  Fly   477 ----HYDTLPTSTSACPASL----NGTIKDISTASPL--FLGSTTEA---PVGEKEFSILDLSFN 528
                ..|:.|..|   |.||    |||.:...|:..|  ...|||:|   .|..:...::.
Mouse   561 EPVAQKDSAPPET---PLSLTLSQNGTTEAPGTSIQLETVQESTTKACGDGVSPRHSKVVR---- 618

  Fly   529 WYTVTGFVITWLIGIPLSYILKSGPDYKPNPKLLSPVVQPFV 570
                   .|.||.|:..:   |..|..|..|.::|....|.|
Mouse   619 -------AILWLCGMEKN---KEEPPSKAEPVIVSLEENPLV 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	144/644 (22%)
Slc5a11	NP_666310.1	SLC5-6-like_sbd	28..673	CDD:382020	151/667 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836511
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740