Protein Alignment Smvt and Slc5a1

DIOPT Version :9

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_062784.3
• Gene: Slc5a1 / 20537
• MGIID: 107678
• Length: 665
• Species: Mus musculus
• Alignment Length: 613
• Identity: 137/613 - (22%)
• Similarity: 255/613 - (41%)
• Gaps: 122/613 - (19%)

  Fly     2 SSLLNATVLATAATVVPDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRM 66
            ||.|:..|.||.|. :|..:.:.||.|..|..:...:..|:|:: ..|:....|...:.:.|:.|
Mouse     3 SSTLSPAVTATDAP-IPSYERIRNAADISVIVIYFVVVMAVGLW-AMFSTNRGTVGGFFLAGRSM 65

  Fly    67 KTIPIAISLVASQLSAISIMTIPAEMYAYGI---NWVFNVVCMVLVVPLLNYLVIPVFYNNNITN 128
            ...||..||.||.:.:...:.:.....|.||   .:.:|.:.:|:|   |.::.:|::....:..
Mouse    66 VWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVLVVV---LGWIFVPIYIKAGVVT 127

  Fly   129 CYEYLEMRFCRKVRVLQTFIFILTMFFMLPIF------IFLPSLAFAQVTGFNVHLINTVVCSIC 187
            ..|||..||..|  .:|.::.:|::  :|.||      ||..::......|.:::|...::.:|.
Mouse   128 MPEYLRKRFGGK--RIQIYLSVLSL--LLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAIT 188

  Fly   188 VFYTMFGGIKAVVWTDVIQAAIM-VASVVLVGVLGAHRVGGFFEVL---------RIAGEGGRLD 242
            ..||:.||:.||::||.:|.||| |.|.:|.| ...:.|||:...:         :::
Mouse   189 ALYTITGGLAAVIYTDTLQTAIMLVGSFILTG-FAFNEVGGYEAFMDKYMKAIPTKVS------- 245

  Fly   243 INYNFD-----LTTRSTIWNIF---TSATMMWTGYV-GL----------NQSCVQRIVSLPSLGH 288
             |.||.     .|.|:..::||   .:..|.|.|.: ||          :|..|||.:|..::.|
Mouse   246 -NGNFTAKEECYTPRADSFHIFRDPITGDMPWPGLIFGLAILALWYWCTDQVIVQRCLSAKNMSH 309

  Fly   289 ARRSLVLFGFGFILIMFFNCFTGI---VIYSRF------HDCDPIQSGHVSKVDKMVPYFVQDTV 344
            .:....|.|:..:|.||.....|:   ::|:..      .:|.......|...:...|..|.:.:
Mouse   310 VKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLVVELM 374

  Fly   345 GNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFD-YIKPHIRHTEHRANVIMKLFVFFTGIYC 408
            .|  |:.|:.:|.:.::.:|:|::..||...:...| |.|...:.:|....:..:||:.
Mouse   375 PN--GLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKASEKELMIAGRLFIL------ 431

  Fly   409 ILGGM------VIENFNS--ILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAA----LVGVLAS 461
            :|.|:      ::::..|  :...|.||..........||:|.:...:.:.:.|    ::|.|..
Mouse   432 VLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGFLIG 496

  Fly   462 IACMATIVILSWGRNHYDTLPTSTSACPASLNGTIKDISTASPLFLGSTTEAPVGEKEFSILDLS 526
            |:.|.|......|.      ....|.||..:.|                              :.
Mouse   497 ISRMITEFAYGTGS------CMEPSNCPKIICG------------------------------VH 525

  Fly   527 FNWYTVTGFVITWLIGIPLSYILKSGPD 554
            :.::.:..|||:.:..:.:|::.|..||
Mouse   526 YLYFAIILFVISVITILIISFLTKPIPD 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	124/580 (21%)
Slc5a1	NP_062784.3	SLC5-6-like_sbd	27..665	CDD:294310	127/588 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7664
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.690