Protein Alignment Smvt and Slc5a6

DIOPT Version :9

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_570102.1
• Gene: Slc5a6 / 170551
• RGDID: 69648
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 200/614 - (32%)
• Similarity: 317/614 - (51%)
• Gaps: 46/614 - (7%)

  Fly     8 TVLATAAT--VVPDSQFV---FNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMK 67
            ||.:|||.  ...|:..|   |:..||.||.|:|.:|..||:|......|..|..|.||..::|.
  Rat     2 TVASTAAPSYTTSDTNRVISTFSVVDYVVFGLLLVLSLVIGLYHACRGWGRHTVGELLMADRKMG 66

  Fly    68 TIPIAISLVASQLSAISIMTIPAEMYAYGINWVFNVVC---MVLVVPLLNYLVIPVFYNNNITNC 129
            .:|:|:||:|:..||::|:..|||:|.:|..:.| :.|   :.|::|.  ::.|||||..::|:.
  Rat    67 CLPVALSLLATFQSAVAILGGPAEIYRFGTQYWF-LGCSYFLGLLIPA--HIFIPVFYRLHLTSA 128

  Fly   130 YEYLEMRFCRKVRVLQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFG 194
            |||||:||.:.||:..|..||..|...:.:.::.||||...||||::.|....:..:|..||..|
  Rat   129 YEYLELRFNKAVRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALG 193

  Fly   195 GIKAVVWTDVIQAAIMVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLD-INYNFDLTTRSTIWNI 258
            |:|||:||||.|..||....::|.::||.:|||...|..:|.:.|.:. |..:.|...|.|.|.:
  Rat   194 GLKAVIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLISGIELDPDPFVRHTFWTL 258

  Fly   259 FTSATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFI----LIMFFNCFTGIVIYSRFH 319
            ......|.....|:||:.|||.:|    .|:.::.||..:...    :.:..:|..|:|:::.:.
  Rat   259 AFGGVFMMLSLYGVNQAQVQRYLS----SHSEKAAVLSCYAVFPCQQVALCMSCLIGLVMFAYYK 319

  Fly   320 DCDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKP 384
            ..........:..|::|.|||.|.:.::.|:||:|::|:||.:|||:|::.|||..|...|.|:|
  Rat   320 KYSMSPQQEQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQP 384

  Fly   385 HI-RHTEHRANVIMKLFVFFTGIYCILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPK 448
            .. :.||.||.::.:...|..|:.|:....|..:..|:||...||.||..|...|:|.|||..|.
  Rat   385 WFPQLTETRAIMLSRSLAFAYGLVCLGMAYVSSHLGSVLQAALSIFGMVGGPLLGLFCLGMFFPC 449

  Fly   449 SHGRAALVGVLASIAC-----MATIVILSWGRNHYDTLPTSTSACPASLNGTIKDISTASPLFLG 508
            ::...|:||:|..:..     :.:||...........|..|:|..|::|  |:..::|..|
  Rat   450 ANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAAASPPLNGSSSFLPSNL--TVATVTTLMP---- 508

  Fly   509 STTEAPVGEKEFSILDLSFNWYT--------VTGFVITWLIGIPLSYILKSGPDYKPNPKLLS-- 563
            ||...|.|.::|  ..||:.||:        ..|.:::.|.|......|..|..|...||||:
  Rat   509 STLSKPTGLQQF--YSLSYLWYSAHNSTTVIAVGLIVSLLTGGMRGRSLNPGTIYPVLPKLLALL 571

  Fly   564 PV-VQPFVHYKLTPSDEPHQLNLEKPEKV 591
            |: .|..:.::....|.|...|| .|||:
  Rat   572 PLSCQKRLCWRSHNQDIPVVTNL-FPEKM 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	176/542 (32%)
Slc5a6	NP_570102.1	SLC5-6-like_sbd	23..548	CDD:382020	176/539 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920