Protein Alignment Smvt and SLC5A10

DIOPT Version :9

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 659
• Identity: 136/659 - (20%)
• Similarity: 256/659 - (38%)
• Gaps: 155/659 - (23%)

  Fly    11 ATAATVVPDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISL 75
            :|:....|.:|  .:..|..|..:..:::.|:|::....| ..:|...|.:.|:.|...||..||
Human     5 STSDLHTPGTQ--LSVADIIVITVYFALNVAVGIWSSCRA-SRNTVNGYFLAGRDMTWWPIGASL 66

  Fly    76 VASQLSAISIMTIPAEMYAYGI---NWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRF 137
            .||...:...:.:.....|.|:   .:.:|...::|.   |.::.:|::.::.|....||::.|:
Human    67 FASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLA---LAWVFVPIYISSEIVTLPEYIQKRY 128

  Fly   138 -CRKVRV-LQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVV 200
             .:::|: |.....:|::|..:.:.::..:|......|:|.:|...:...|...||:.||:.||:
Human   129 GGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVI 193

  Fly   201 WTDVIQAAIMVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLDINYNFDLTTRSTIWNIF-----T 260
            :||.:|..|||...|::.:....::||:          |:|:..|...:.:| ||.|..     |
Human   194 YTDALQTLIMVVGAVILTIKAFDQIGGY----------GQLEAAYAQAIPSR-TIANTTCHLPRT 247

  Fly   261 SATMM----------WTG-----------YVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIM 304
            .|..|          |||           |...:|..|||.:|...|.||:...:|..:..:|.|
Human   248 DAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPM 312

  Fly   305 FFNCFTGIVIYSRFHDCDPIQSGH---VSKVDKM----------------------VPYFVQDTV 344
            ......|::..:.|......:..|   ||:.|.:                      .|..|.:.:
Human   313 GLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELM 377

  Fly   345 GNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDY---IKPHIRHTE---------------- 390
            .  .|:.|:.|:.:.:|.:|:|::..||...:...|.   ::|.....|
Human   378 P--IGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRTGIPSTPPAP 440

  Fly   391 -HRAN----------------VIMKLFVFFTGIYCILGGM-----VIENFNSILQVIY--SIGGM 431
             .|.:                |:|.|::.   |..::|..     |:::.||....||  |:...
Human   441 QSRLSFLLPETPPLERYLLGLVVMDLWLV---IVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSS 502

  Fly   432 SFGSTCGVFMLGMLVPKSHGRAALVGVLASIACMATIVILSWGR-----NHYDTLPTSTSACPAS 491
            .......||:||:...:::.:.|..|::|.:...||.::|.:..     ...||.|        :
Human   503 LAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRP--------A 559

  Fly   492 LNGTIKDISTASPLF--------LGSTTEAPVGEKEFSILDLSFNWYTVTGFVITWLIGIPLSYI 548
            :.|:|..:..|..||        .||....|....:..    :..|:|:..       .:||.
Human   560 VLGSIHYLHFAVALFALSGAVVVAGSLLTPPPQSVQIE----NLTWWTLAQ-------DVPLG-- 611

  Fly   549 LKSGPDYKP 557
            .|:|....|
Human   612 TKAGDGQTP 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	130/632 (21%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:320982	133/645 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146413
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740