Protein Alignment Smvt and Slc5a5

DIOPT Version :10

• Sequence 1: NP_651891.2
• Gene: Smvt / 43744
• FlyBaseID: FBgn0039873
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_443215.2
• Gene: Slc5a5 / 114613
• RGDID: 69267
• Length: 618
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 190/618 - (30%)
• Similarity: 300/618 - (48%)
• Gaps: 75/618 - (12%)

  Fly    24 FNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTI 88
            |.|.||||||.:|.:|..||::.|....|:.:.:::..||:::..:|:.:||.||.:||:.::.:
  Rat    12 FGAWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGV 76

  Fly    89 PAEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQTFIFILTM 153
            |||...||:.:::.....:|...|..:|.:|:||...:|:.|:|||:||.|.||:..|..:::..
  Rat    77 PAEAARYGLKFLWMCAGQLLNSLLTAFLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVAT 141

  Fly   154 FFMLPIFIFLPSLAFAQVTGFNV--HLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVL 216
            .....|.|:.|:|...||||.::  .|::|.:  ||..||..||:||||||||.|..:|:....:
  Rat   142 MLYTGIVIYAPALILNQVTGLDIWASLLSTGI--ICTLYTTVGGMKAVVWTDVFQVVVMLVGFWV 204

  Fly   217 VGVLGAHRVGGFFEVLRIAGEGGRLDI-NYNFDLTTRSTIWNIFTSATMMWTGYVGLNQSCVQRI 280
            :...|...:||...:|.:|....|::: :::.|..:|.|.|......|::|....|:||:.|||.
  Rat   205 ILARGVILLGGPRNMLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGGTLVWLSMYGVNQAQVQRY 269

  Fly   281 VSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTVG 345
            |:..:.|.|:.:|::...|..||:......|||::..:.||||:.:|.:|..|:.:|..|.|...
  Rat   270 VACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFE 334

  Fly   346 NLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKPHIRHTEHRANV-IMKLFVFFTGIYC- 408
            :|.|:||:|::|.:|..|||.|.|||::..|...|.|||.:.....|..| |.|...|..|..|
  Rat   335 DLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPGLAPRKLVFISKGLSFIYGSACL 399

  Fly   409 -------ILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVGVLASIACMA 466
                   :|||       .:||..:::.|:..|...|.|.||||:|..:....|.|:.|.:|...
  Rat   400 TVAALSSLLGG-------GVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLAAGLAVSL 457

  Fly   467 TIVILSW----GRNHYDTLPTSTSAC---------PASLNGTIKDISTASPLFLGSTTEAPVGEK 518
            .:.:.:.    |......||||.:.|         |.:.|.     |...| ..|..|..|....
  Rat   458 WVAVGATLYPPGEQTMGVLPTSAAGCTNDSVLLGPPGATNA-----SNGIP-SSGMDTGRPALAD 516

  Fly   519 EFSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPDYKPN--PKLL------------------- 562
            .|  ..:|:.:|...|.:.|.|.|..:||:  :||..:.:  |.||
  Rat   517 TF--YAISYLYYGALGTLTTMLCGALISYL--TGPTKRSSLGPGLLWWDLARQTASVAPKEDTAT 577

  Fly   563 -------SPVVQPFVHYK---LTPSDEPHQLNL 585
                   .|...|.|..|   |.|..|.|.|.|
  Rat   578 LEESLVKGPEDIPAVTKKPPGLKPGAETHPLYL 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	172/545 (32%)
Slc5a5	NP_443215.2	SLC5sbd_NIS	15..549	CDD:271393	175/552 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	587..618		9/24 (38%)