DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Smvt and slc5a7a

DIOPT Version :9

Sequence 1:	NP_651891.2	Gene:	Smvt / 43744	FlyBaseID:	FBgn0039873	Length:	591	Species:	Drosophila melanogaster
Sequence 2:	XP_021332411.1	Gene:	slc5a7a / 100005589	ZFINID:	ZDB-GENE-090313-273	Length:	592	Species:	Danio rerio

Alignment Length:	491	Identity:	91/491 - (18%)
Similarity:	179/491 - (36%)	Gaps:	122/491 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GVFALVL--SISAAIGVYFGFFAK------GEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIM 86
            |:.|:|:  .:...:|::..:..|      |.|.:|..::||:.:.....|.::.|:.:....|.
Zfish     7 GLVAIVIFYLLILLVGIWAAWKNKNSGVMEGTDRSETIMVGGRDIGLFVGAFTMTATWVGGGYIN 71

  Fly    87 TIPAEMY--AYGINWV---FNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQT 146
            .....:|  .:|:.|.   |.....:::..|  :...|:.....:|....:.::...|...:|..
Zfish    72 GTAEYVYLPGFGLAWAQAPFGYALSLVLGGL--FFAKPMRSRGYVTMLDPFQQLYGKRMGGLLFI 134

  Fly   147 FIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQA---- 207
            ...:..||:...|...| ....:.:...::::...:...|.:|||:.||:.:|.:|||:|.
Zfish   135 PALMGEMFWSAAILSAL-GATLSVIIDIDINMSVVISALIAIFYTLVGGLYSVAYTDVVQLFCIF 198

  Fly   208 ---------AIMVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLDINYNFDLTTRSTIW--NIFTS 261
                     |:...:|..:||....:                        |....|.|  .|.:|
Zfish   199 LGLWVSVPFALSNPAVSDIGVTAVKQ------------------------LHANQTAWLGKIESS 239

  Fly   262 ATMMWTGYVGLNQSCV------------QRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVI 314
            ...||.     :..|:            ||::|..|..:|:....|..||.|::...:...|.:.
Zfish   240 DKWMWA-----DNFCLLMLGGIPWQVYFQRVLSASSATYAQVLSFLAAFGCIIMAIPSVLIGAIG 299

  Fly   315 YS------RFHDCDPIQSGHVSKVDKMVPYFVQDTVG---NLWGMPGVFISCVFSAALSTLSASI 370
            .|      .:....|:|.   .:.|.::|..:|....   :.:|:..|..:.:.||..|.||||.
Zfish   300 ASTDWNQTSYGPIPPMQK---DQSDMILPIVLQHLCPAYISFFGLGAVSAAVMSSADSSILSASS 361

  Fly   371 NSLGGVVYFDYIKPHIRHTEHRANVI----MKLFVF---------FTG------------IYCIL 410
            .....:....:     |.:.....::    :.:|||         .||            :|.|:
Zfish   362 MFARNIYQLAF-----RQSASDREIVWVMRITIFVFGALATAMALLTGTVYGLWYLSSDLVYVII 421

  Fly   411 GGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLV 446
                   |..:|.|::..|..::||..|.| .|:::
Zfish   422 -------FPQLLSVLFIRGTNTYGSVAGYF-FGLIL 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smvt	NP_651891.2	SLC5sbd_NIS-SMVT	27..548	CDD:271383	91/491 (19%)
slc5a7a	XP_021332411.1	SLC5sbd_CHT	8..508	CDD:271368	90/490 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580022
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840