Protein Alignment CG2187 and DUR3

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_011847.1
• Gene: DUR3 / 856370
• SGDID: S000001008
• Length: 735
• Species: Saccharomyces cerevisiae
• Alignment Length: 648
• Identity: 136/648 - (20%)
• Similarity: 255/648 - (39%)
• Gaps: 155/648 - (23%)

  Fly    30 FVFVIMLGA-SAGIGVYFGF----FSKSKNTTEEYLRGGKKMQTLPIAISLVASQLSGIAIMSIP 89
            :..|:.||| .||:.|...:    :.|...|.||:...|:.::|..:|.::|:|.:....:::..
Yeast    14 YAIVLGLGAVFAGMMVLTTYLLKRYQKEIITAEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSS 78

  Fly    90 AESYTYGF--NYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEM---RFNKRTRQLVTFFF 149
            .:.|..|.  .|.:...|   ...|:.:.|:.:..:....|.:.|||:   |:.|.......|:.
Yeast    79 TKEYADGIFGGYAYAAGA---CFQIIAFAILAIKTKQMAPNAHTYLELVRTRYGKIGHGCYLFYA 140

  Fly   150 VTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSV 214
            :..:.|:..:.:...|..|:.:||||......::....:.||:.|||||...||.:...::::.|
Yeast   141 IATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIIIIV 205

  Fly   215 VAVG--------VLGTIRSGGMFTVMERASD----GGRFNFDFGLDPRIRMTFWGATMGGIFMWT 267
            :...        |||:  .|.::.::..|:.    .|.:..::     :.||...|.:..|....
Yeast   206 LVFAFKVYATSDVLGS--PGKVYDLVREAAKRHPVDGNYQGEY-----MTMTSKSAGILLIINLI 263

  Fly   268 GHIG---LNQSCVQRIVSLPSYSHAKKSLIVSGLG-FLIISFFNTISGIIM--------FARYYG 320
            |:.|   |:.....:.:| .|.:.:.|:..:.||. |.:.|..:...|:..        |..|
Yeast   264 GNFGTVFLDNGYWNKAIS-ASPAASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPNFPTY-- 325

  Fly   321 CDPML-----AGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGV---- 376
            .||:.     :|||      :|.....|||....:..:.:  :|.|..|::||.|.:::.|
Yeast   326 PDPLTSFQANSGLV------LPAAAIAIMGKGGAVASLLM--IFMAVTSAMSAELIAVSSVFTYD 382

  Fly   377 VYFDYIKPRIRHTEARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFL 441
            :|.:||.||.         :.|.::......||..|             :.::|.:.|...|...
Yeast   383 IYREYIDPRA---------SGKKLIYTSHVACIFFG-------------LAMSGFSVGLYYGGIS 425

  Fly   442 LGMFVPRCNAKTAVTSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAIN 506
            :|.                 :..|:.||           |...|||..|..| ::.:.::|..:
Yeast   426 MGY-----------------IYEMMGII-----------ISSAVLPVVLTLC-SKDMNLVAAVV- 460

  Fly   507 KTDFTPVTMKPPSGAPVTTAFHSDRDFSLY-----DISFYWYKVLGSALVFLCA----IP-LSYI 561
                :|:.   .:|..:.:.....:  |||     |.:|..|.:|...||.|.:    || |:|:
Yeast   461 ----SPIL---GTGLAIMSWLVCTK--SLYKELTVDTTFMDYPMLTGNLVALLSPAIFIPILTYV 516

  Fly   562 WRPDENEKQNPKLYSPFVRKFLSLPVTDQDLEEVPLRGSKVAATPDLRI---EPTEKEKQTVT 621
            ::|...:.:..|                 |:..|......|.|.||:::   |..:||::..|
Yeast   517 FKPQNFDWEKMK-----------------DITRVDETAELVQADPDIQLYDAEANDKEQEEET 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	123/583 (21%)
DUR3	NP_011847.1	SLC5sbd_DUR3	14..517	CDD:271370	124/584 (21%)