Protein Alignment CG2187 and Slc5a7

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_445973.2
• Gene: Slc5a7 / 85426
• RGDID: 69270
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 626
• Identity: 124/626 - (19%)
• Similarity: 227/626 - (36%)
• Gaps: 178/626 - (28%)

  Fly    25 GLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEE----YLRGGKKMQTLPIAISLVASQLSGIAI 85
            ||....:|.:::..   :|::..:.:|:....||    .:.||:.:..|....::.|:.:.|..|
  Rat     7 GLVAIILFYLLIFL---VGIWAAWKTKNSGNAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYI 68

  Fly    86 MSIPAESYTYGFNYIFVVLAMLVVIPIL---IYIIVPVFYENNVSNCYEYLEMRFNKRTRQLVTF 147
            .......|..|....:....:...:.::   ::...|:..:..|:....:.:: :.||...|
  Rat    69 NGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQI-YGKRMGGL--- 129

  Fly   148 FFVTNSFLMLPVYMFIPSL--------AFAQVTGMNIHL-------INVMVSS-ICIFYTMLGGI 196
                         :|||:|        |.....|..|.:       |:|:||: |.|.||::||:
  Rat   130 -------------LFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGL 181

  Fly   197 KAVVWTDVVQ------------------GAIMLLSVVAVGV------LGTIRSGGMFTVMERASD 237
            .:|.:|||||                  .|:..:...||..      ||||.|..::|.::
  Rat   182 YSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESIEVYTWLD---- 242

  Fly   238 GGRFNFDFGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLI 302
                            .|....:||| .|       |:..||::|..|.::|:....::..|.|:
  Rat   243 ----------------NFLLLMLGGI-PW-------QAYFQRVLSSSSATYAQVLSFLAAFGCLV 283

  Fly   303 ISFFNTISGIIMFA-----RYYGC-DPMLAGLVSKPDKMMPFFVQ---DIMGHLAGMPGVFISCV 358
            ::......|.|..:     ..||. ||...   .:.|.::|..:|   .:.....|: |...:.|
  Rat   284 MALPAICIGAIGASTDWNQTAYGFPDPKTK---EEADMILPIVLQYLCPVYISFFGL-GAVSAAV 344

  Fly   359 FSAALSSLSATLNSLAGVVYFDYIKPRIRHTEARANWAMKLIVVVMGGYCILGGFMVQNFNSI-- 421
            .|:|.||:.:..:..|..:|  .:..|...::....|.|::.|.|.|........:.:....:
  Rat   345 MSSADSSILSASSMFARNIY--QLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWY 407

  Fly   422 -------------LQTVVTITGINT-GAVVGVFLLGMFV---------------------PRCNA 451
                         |..|:.|.|.|| |||.| ::.|:|:                     |..|.
  Rat   408 LSSDLVYIIIFPQLLCVLFIKGTNTYGAVAG-YIFGLFLRITGGEPYLYLQPLIFYPGYYPDKNG 471

  Fly   452 --------KTAVTSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEA-----------RG 497
                    ||  .|::.|....:.:....:..|:||     .||..||..:|           :.
  Rat   472 IYNQRFPFKT--LSMVTSFFTNICVSYLAKYLFESG-----TLPPKLDIFDAVVSRHSEENMDKT 529

  Fly   498 LYMIAEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFSLYDI 538
            :.:..|.|...:..||  ||.....:::.|.:..  :|.|:
  Rat   530 ILVRNENIKLNELAPV--KPRQSLTLSSTFTNKE--ALLDV 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	122/624 (20%)
Slc5a7	NP_445973.2	SLC5sbd_CHT	8..495	CDD:271368	106/543 (20%)
		Mediates interaction with SEC14L1. /evidence=ECO:0000269|PubMed:17092608	502..580		17/74 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340171
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740