Protein Alignment CG2187 and SLC5A4

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_016884409.1
• Gene: SLC5A4 / 6527
• HGNCID: 11039
• Length: 689
• Species: Homo sapiens
• Alignment Length: 468
• Identity: 105/468 - (22%)
• Similarity: 196/468 - (41%)
• Gaps: 58/468 - (12%)

  Fly    52 SKNTTEEYLRGGKKMQTLPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYI 116
            ::.|...:...|:.|...|:..||.||.:.....:.:.......|...:.......|::.||.:|
Human    81 NRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWI 145

  Fly   117 IVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSF----LMLPVYMFIPSLAFAQVTGMNIH 177
            .||::.::.|....|||:.||.  ..:|..:..:.:.|    |::...:|..::......|::::
Human   146 FVPIYIKSGVMTMPEYLKKRFG--GERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDLY 208

  Fly   178 LINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLL-SVVAVGVLGTIRSGGMFTVMER------- 234
            |...::.::...||..||:.:|::||.:|..|||: |.:.:| ......||..:..|:
Human   209 LAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMG-FAFNEVGGYESFTEKYVNATPS 272

  Fly   235 ASDGGRFNFDFG-LDPRIRM--TFWGATMGGIFMWTGHI-GL----------NQSCVQRIVSLPS 285
            ..:|........ ..||...  .|..|..|.| .|.|.| |:          ||..|||.:....
Human   273 VVEGDNLTISASCYTPRADSFHIFRDAVTGDI-PWPGIIFGMPITALWYWCTNQVIVQRCLCGKD 336

  Fly   286 YSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCDPMLAGLVSKPDKMM-------------- 336
            .||.|.:.|:.....|:..|...:.|:|....|   ..|:|.:|  |.:.:
Human   337 MSHVKAACIMCAYLKLLPMFLMVMPGMISRILY---TDMVACVV--PSECVKHCGVDVGCTNYAY 396

  Fly   337 PFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFD-YIKPRIRHTEARANWAMKLI 400
            |..|.::|..  |:.|:.:|.:.::.:|||::..||.:.:...| |.|.|.:.:|.....|.::.
Human   397 PTMVLELMPQ--GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIF 459

  Fly   401 VVVMGGYCILGGFMVQ--NFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIV--- 460
            |:::....|:...:||  ....::....:|:......:..||:|.:|..|.|.:.|...::|
Human   460 VLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWGLMVGLA 524

  Fly   461 -SVVAMVWIIANG 472
             .::.|:...|.|
Human   525 MGLIRMITEFAYG 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	105/468 (22%)
SLC5A4	XP_016884409.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146417
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740