Protein Alignment CG2187 and Slc5a2

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_072112.2
• Gene: Slc5a2 / 64522
• RGDID: 620217
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 120/517 - (23%)
• Similarity: 202/517 - (39%)
• Gaps: 144/517 - (27%)

  Fly    29 YFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISLVASQL------------- 80
            ||:.||      |:|:: ..|..::.|...|...|:.|...|:..||.||.:
  Rat    30 YFLLVI------GVGLW-SMFRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGA 87

  Fly    81 -SGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFNKRTRQL 144
             ||:|:..       :.:|.:||||       :|.::.|||:....|....:||..||..|..:|
  Rat    88 ASGLAVAG-------FEWNALFVVL-------LLGWLFVPVYLTAGVITMPQYLRKRFGGRRIRL 138

  Fly   145 V-----TFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDV 204
            .     .|.::   |..:.|.||..::...|..|.||:...:.:..|.:.||:.||:.|:::||.
  Rat   139 YLSVLSLFLYI---FTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDT 200

  Fly   205 VQ------------------------------GAIMLLSVVAVGVLGTIRSGGMFTVMERASDGG 239
            ||                              ||:..|:|.....:|.|.|    |..:...|
  Rat   201 VQTFVILAGAFILTGYAFHEVGGYSGLFDKYLGAVTSLTVSKDPAVGNISS----TCYQPRPD-- 259

  Fly   240 RFNFDFGLDPRIRMTFWGATMGGIFMWTG-HIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLII 303
              ::....||......|.|.:.|:.:.:| :...:|..|||.::..:.:|.|...|:.|...|:.
  Rat   260 --SYHLLRDPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKNLTHIKAGCILCGYLKLMP 322

  Fly   304 SFFNTISGIIMFARY-------------------YGCD----PMLAGLVSKPDKMMPFFVQDIMG 345
            .|...:.|:|....|                   .||.    |.|.      .|:||
  Rat   323 MFLMVMPGMISRILYPDEVACVVPEVCKRVCGTEVGCSNIAYPRLV------VKLMP-------- 373

  Fly   346 HLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDY---IKPRIRHTE---ARANWAMKLIVVVM 404
              .|:.|:.::.:.:|.:|||::..||.:.:...|.   ::||....|   ....|.:.::.|.:
  Rat   374 --NGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVAVSV 436

  Fly   405 GGYCIL----GGFM---VQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSII 459
            ....::    ||.:   :|:.:|.|...|:          .||:|.:||||.|.|.|...:|
  Rat   437 AWLPVVQAAQGGQLFDYIQSVSSYLAPPVS----------AVFVLALFVPRVNEKGAFWGLI 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	120/517 (23%)
Slc5a2	NP_072112.2	SLC5-6-like_sbd	22..670	CDD:444915	120/517 (23%)