Protein Alignment CG2187 and Slc5a7

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_071308.2
• Gene: Slc5a7 / 63993
• MGIID: 1927126
• Length: 580
• Species: Mus musculus
• Alignment Length: 626
• Identity: 123/626 - (19%)
• Similarity: 227/626 - (36%)
• Gaps: 178/626 - (28%)

  Fly    25 GLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEE----YLRGGKKMQTLPIAISLVASQLSGIAI 85
            ||....:|.:::..   :|::..:.:|:....||    .:.||:.:..|....::.|:.:.|..|
Mouse     7 GLVAIILFYLLIFL---VGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYI 68

  Fly    86 MSIPAESYTYGFNYIFVVLAMLVVIPIL---IYIIVPVFYENNVSNCYEYLEMRFNKRTRQLVTF 147
            .......|..|....:....:...:.::   ::...|:..:..|:....:.:: :.||...|
Mouse    69 NGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQI-YGKRMGGL--- 129

  Fly   148 FFVTNSFLMLPVYMFIPSL--------AFAQVTGMNIHL-------INVMVSS-ICIFYTMLGGI 196
                         :|||:|        |.....|..|.:       |:|:||: |.|.||::||:
Mouse   130 -------------LFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGL 181

  Fly   197 KAVVWTDVVQ------------------GAIMLLSVVAVGV------LGTIRSGGMFTVMERASD 237
            .:|.:|||||                  .|:..:...||..      ||||.|..::|.::
Mouse   182 YSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLD---- 242

  Fly   238 GGRFNFDFGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLI 302
                            .|....:||| .|       |:..||::|..|.::|:....::..|.|:
Mouse   243 ----------------NFLLLMLGGI-PW-------QAYFQRVLSSSSATYAQVLSFLAAFGCLV 283

  Fly   303 ISFFNTISGIIMFA-----RYYGC-DPMLAGLVSKPDKMMPFFVQ---DIMGHLAGMPGVFISCV 358
            ::......|.|..:     ..||. ||...   .:.|.::|..:|   .:.....|: |...:.|
Mouse   284 MALPAICIGAIGASTDWNQTAYGYPDPKTK---EEADMILPIVLQYLCPVYISFFGL-GAVSAAV 344

  Fly   359 FSAALSSLSATLNSLAGVVYFDYIKPRIRHTEARANWAMKLIVVVMGGYCILGGFMVQNFNSI-- 421
            .|:|.||:.:..:..|..:|  .:..|...::....|.|::.|:|.|........:.:....:
Mouse   345 MSSADSSILSASSMFARNIY--QLSFRQNASDKEIVWVMRITVLVFGASATAMALLTKTVYGLWY 407

  Fly   422 -------------LQTVVTITGINT-GAVVGVFLLGMFV-------------------------- 446
                         |..|:.|.|.|| |||.| ::.|:|:
Mouse   408 LSSDLVYIIIFPQLLCVLFIKGTNTYGAVAG-YIFGLFLRITGGEPYLYLQPLIFYPGYYSDKNG 471

  Fly   447 ---PRCNAKTAVTSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEA-----------RG 497
               .|...||  .|::.|....:.:....:..|:||     .||..||..:|           :.
Mouse   472 IYNQRFPFKT--LSMVTSFFTNICVSYLAKYLFESG-----TLPPKLDVFDAVVARHSEENMDKT 529

  Fly   498 LYMIAEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFSLYDI 538
            :.:..|.|...:..||  ||.....:::.|.:..  :|.|:
Mouse   530 ILVRNENIKLNELAPV--KPRQSLTLSSTFTNKE--ALLDV 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	121/624 (19%)
Slc5a7	NP_071308.2	SLC5sbd_CHT	8..495	CDD:271368	105/543 (19%)
		Mediates interaction with SEC14L1. /evidence=ECO:0000250|UniProtKB:Q9JMD7	502..580		17/74 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740