Protein Alignment CG2187 and slc5a9

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001107077.1
• Gene: slc5a9 / 564815
• ZFINID: ZDB-GENE-080513-3
• Length: 657
• Species: Danio rerio
• Alignment Length: 671
• Identity: 153/671 - (22%)
• Similarity: 260/671 - (38%)
• Gaps: 162/671 - (24%)

  Fly    29 YFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISLVASQLS-----GIAIMSI 88
            |||||:.:|..:.|       ..::.|...|...|:.|...||..||::|.:.     |:|....
Zfish    34 YFVFVLAVGIWSSI-------RANRGTVGGYFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGA 91

  Fly    89 PAESYTYGF--NYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRF-NKRTRQLVTFFFV 150
            .......||  |..:|::|       |.:|.|||:....|....|||..|| .:|.|       :
Zfish    92 AGGLAVGGFEWNAAWVLIA-------LGWIFVPVYISAGVVTMPEYLRKRFGGQRIR-------I 142

  Fly   151 TNSFLMLPVYM-------FIPSLAFAQVT-GMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQG 207
            ..|.|.|.:|:       ......|.||: |.:::|..|::.::...||:.||:.||::||.:|.
Zfish   143 YMSVLSLILYILTKISTDIFSGALFIQVSLGWDLYLSTVILLAVTALYTIAGGLTAVIYTDALQT 207

  Fly   208 AIMLLSVVAVGVLGTIRSG---GMFTVMERA---------------SDGGRFNFDFGLDPRIRMT 254
            .||::....:..:...:.|   |:....|:|               ||.    |....||.....
Zfish   208 VIMVIGAFVLMFIAFDKVGWYEGLLVQYEKAAPALTVPNTTCHLPRSDA----FHIFRDPVTGDI 268

  Fly   255 FW-----GATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTISGIIM 314
            .|     |.|:...::|.    .:|..|||.:|..:.||||...::.|...:...||..:.|:|.
Zfish   269 PWPGLIFGLTVLATWVWC----TDQVIVQRSLSAKNLSHAKAGSVLGGYLKVFPMFFVVMPGMIS 329

  Fly   315 FARYYG---------CDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATL 370
            .|.|..         |..:....|...:...|..|.::|.  .||.|:.|:.:.:|.:|||::..
Zfish   330 RALYPDEVACVDPDECQKICGAKVGCSNIAYPKLVVELMP--VGMRGLMIAVMMAALMSSLTSIF 392

  Fly   371 NSLAGVVYFDY---IKPRIRHTEARANWAMKLIVVVMGGYCILGGFMVQNFNS--ILQTVVTITG 430
            ||.:.:...|.   |:||....|...  ..::.::::....|:...::|..||  :...:..||.
Zfish   393 NSSSTLFTMDIWQRIRPRASEKELMV--VGRVFILLLVALSIVWIPVIQTANSGQLFDYIQAITS 455

  Fly   431 INTGAVVGVFLLGMFVPRCNAKTAVTSIIVS-VVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCE 494
            ..:..:..||::.:|..|.|.:.|...::|. ||.||.:|    |.|..|
Zfish   456 FLSPPITTVFIMAIFWGRVNEQGAFWGLMVGLVVGMVRMI----MEFVYG--------------- 501

  Fly   495 ARGLYMIAEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFSLYDISFYWYKVLGSAL-------VF 552
                   ..:..:||..|..:|                    |:.:.::.::..||       |.
Zfish   502 -------TPSCGETDLRPSLLK--------------------DVHYLYFALILLALTVLIITAVS 539

  Fly   553 LCAIPL------SYIWRPDENEKQNPKLYSPFVR---KFLSLPVTDQDLEEVP---------LRG 599
            ||..|:      ...|....::::..:|..|:.:   ..||...::...|:.|         |.|
Zfish   540 LCTAPIPEKHLVRLTWWTRHSKEERVELEDPWAKPAGSDLSTTESEGSDEDAPAWWKRAGMWLCG 604

  Fly   600 SKVAATPDLRIEPTEKEKQTV 620
            .......||    ||:|:|.:
Zfish   605 LSQTTKQDL----TEEERQAL 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	138/598 (23%)
slc5a9	NP_001107077.1	SLC5sbd_SGLT4	42..657	CDD:271380	148/663 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740