Protein Alignment CG2187 and slc5a11

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001007301.1
• Gene: slc5a11 / 492334
• ZFINID: ZDB-GENE-041114-9
• Length: 668
• Species: Danio rerio
• Alignment Length: 685
• Identity: 147/685 - (21%)
• Similarity: 266/685 - (38%)
• Gaps: 182/685 - (26%)

  Fly     2 STTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKM 66
            ::.|.|:...|...:.|:.|: ..|..||:.|:.:|       .:..:...::|.:.|...||.|
Zfish     9 ASPTPTSDGTAQQTTLATTDI-VVLVIYFLLVLAVG-------LWSMWKTKRSTVDGYFLAGKNM 65

  Fly    67 QTLPIAISLVASQL----------SGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVF 121
            ...|:..||.||.:          || |...|.|.:|.:.        .||:|: ::.::.:|::
Zfish    66 TWWPVGASLFASNVGSGHFIGLAGSG-AAAGIGAVAYEWN--------GMLMVL-VMGWLFLPIY 120

  Fly   122 YENNVSNCYEYLEMRFNKRTRQL---VTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMV 183
            ..:.|:...|||:.||..:..||   |.:.|: ..|..:.|.|:..::...|....||:|..|::
Zfish   121 IASRVTTMPEYLKKRFGGKRIQLFLCVLYLFI-YIFTKISVDMYAGAVFIQQALQWNIYLAVVLL 184

  Fly   184 SSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFNFDFGLD 248
            ..|...||:.||:.||::||.||..||::..:.:........||...|:::....         .
Zfish   185 LGITALYTIAGGLAAVIYTDAVQTIIMVIGALILMGFSFAEVGGFEAVLDKYPQA---------I 240

  Fly   249 PRIRM--TFWGATMGGIF-----------MWTGHI-GL----------NQSCVQRIVSLPSYSHA 289
            |.||:  |..|......|           .|.|.| |:          :|..|||.::..:..||
Zfish   241 PSIRVPNTTCGIPRDDAFHIFRHPVTSDLPWPGVILGMSIPSMWYWCSDQVIVQRSLAAKNILHA 305

  Fly   290 KKSLIVSGLGFLIISFFNTISGI---IMFARYYGC-DP-----MLAGLVSKPDKMMPFFVQDIMG 345
            |...:::....::..|...|.|:   |::....|| ||     :....|...|......|.:::.
Zfish   306 KGGSLLAAYIKVLPFFMMVIPGMISRILYPDEVGCGDPEVCKEVCGNSVGCSDIAYAKLVMELLP 370

  Fly   346 HLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIRHTEARANWAMKLI----VVVMGG 406
              ||:.|:.::.:.:|.:|||::..||.:.:...|..: .||||  .:.|.:.::    |:|:..
Zfish   371 --AGLRGLMMAVMLAALMSSLTSIFNSSSTIFTMDLWR-NIRHT--ASEWELMIVGRVFVLVLVV 430

  Fly   407 YCIL---------GG---FMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTA----- 454
            ..:|         ||   ..:|:.:..||..:|:          :|:.|.|..|.|.|.|
Zfish   431 VSVLWIPLVQASQGGQLFIYIQSISMYLQPPITV----------IFVAGCFWKRTNEKGAFWGLM 485

  Fly   455 -------------------------------------VTSIIVSVVAMVWIIANG---------Q 473
                                                 ..|||::::.:|.::...         |
Zfish   486 VGMAVGCTRMILDFIYPTPQCYESDTRPDIIKYVHFLYFSIILTILTLVVVVCVSLATEKPKPEQ 550

  Fly   474 MNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFSLYDI 538
            ::..:...:::.:..| ::..:..||.|...|...:...:..|..|...|::...|.:
Zfish   551 ISRLTWYTRFDAVIES-EEVVSSELYTIDNDIKVRENEALPAKEDSSGSVSSNAGSSK------- 607

  Fly   539 SFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPK 573
                   |.|||.:||.:           |||..|
Zfish   608 -------LKSALFWLCGM-----------EKQTEK 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	137/646 (21%)
slc5a11	NP_001007301.1	SLC5sbd_SGLT6	28..668	CDD:271381	143/666 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740