Protein Alignment CG2187 and LOC4576984

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_001238431.3
• Gene: LOC4576984 / 4576984
• VectorBaseID: AGAMI1_003923
• Length: 634
• Species: Anopheles gambiae
• Alignment Length: 643
• Identity: 195/643 - (30%)
• Similarity: 348/643 - (54%)
• Gaps: 56/643 - (8%)

  Fly     2 STTTTT----TTTMASAVSSASQDL-RFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTE---- 57
            ||..||    :......:.|.|:.| ||...||.|||:||.....||::||:....|:...
Mosquito    16 STDETTSFEESEPPGQTIDSISRSLQRFDWPDYVVFVLMLLICIVIGIFFGYKDHQKHKHRRKQA 80

  Fly    58 -------EYLRGGKKMQTLPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIY 115
                   :||.||:|||..|:::|||||.:|||:::....|.|.||..|.::|.|::::..::.:
Mosquito    81 RRESEALDYLVGGRKMQIFPVSVSLVASWISGISLLGTSTEIYVYGTQYCYIVFAVIMMGFVMHH 145

  Fly   116 IIVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLIN 180
            :.:|||:|..:::.||||:.||:.|.|...:..|.....|.:|:.:::|:|||.|||||:||::.
Mosquito   146 VFLPVFHELQITSAYEYLQRRFDHRMRLFGSILFTVACLLWMPIVIYVPALAFNQVTGMSIHIVT 210

  Fly   181 VMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFNFD- 244
            .:|..||:|||.:||:||||||||:|..:.||:::||.:.||...||...|::|...|||....
Mosquito   211 PIVCMICVFYTSIGGLKAVVWTDVIQSGVTLLALLAVLIKGTYDVGGPAEVVQRNIAGGRLEAPI 275

  Fly   245 FGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTI 309
            |..||.:|.:.|...:|....:...:..:|..:||.::||:...|:|:|....:|:::::....:
Mosquito   276 FDPDPTLRHSIWIILLGAPVWFCYGVSCSQDMIQRFLALPTLQDARKALKGFVIGWIVVNVIFFL 340

  Fly   310 SGIIMFARYYGCDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLA 374
            .|::::|.||.|||:...|....|:::|.||.:......||.|||::.:|||||||||:.||:|:
Mosquito   341 IGMLVYATYYRCDPLTTQLARAKDQLLPLFVMETFAAYPGMTGVFVAGIFSAALSSLSSALNALS 405

  Fly   375 GVVYFDYIKPRIRH--TEARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVV 437
            .:...|:.||..:.  ||.:.|:.|:..|:|.|...:|...:|::..:::|..:|::..:...:.
Mosquito   406 AITLEDFFKPYCKKPLTEKQINYIMRGSVLVYGALSVLLSILVEHLGTVMQLTMTLSSASGAPLF 470

  Fly   438 GVFLLGMFVPRCNAKTAVTSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIA 502
            |:|::|:.:|..|...|:...:..::.|:::....|.:..||...::..|.|::.|
Mosquito   471 GLFVMGILMPWVNGTGALYGGVTGLLVMLYMCYKAQYSIASGSRSFDTKPVSVEDC--------- 526

  Fly   503 EAINKTDFTPVTMKPPSGAPVTTAFHSD------RDFSLYDISFYWYKVLGSALVFLCAIPLSYI 561
                ..|:         |...|.....|      .:.|:|.:|:.::.:.|:::..|....:|.:
Mosquito   527 ----PYDY---------GRNATMGLIEDDAELEQLEKSIYHMSYMYFTLFGTSVTCLTGTVVSLL 578

  Fly   562 WR---PDENEKQNPKLYSPFVRKF--LSLPVTDQDLEEVPLRGSKVAATPDLRIEPTE 614
            .:   .|.::..:|||.:|.:|:.  ..:|:|   .:.|| ..:|.|...:..::.||
Mosquito   579 TKLCGSDRDQPIDPKLLAPCIRRIQPRDIPLT---FQSVP-TDNKQAEASEAALKRTE 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	172/553 (31%)
LOC4576984	XP_001238431.3	None