Protein Alignment CG2187 and slc5a6

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_031757499.1
• Gene: slc5a6 / 448188
• XenbaseID: XB-GENE-5737332
• Length: 638
• Species: Xenopus tropicalis
• Alignment Length: 585
• Identity: 182/585 - (31%)
• Similarity: 300/585 - (51%)
• Gaps: 58/585 - (9%)

  Fly    22 LRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISLVASQLSGIAIM 86
            :||...||.:||::|..|:.||:|:......:.|.:|:|...:.|..|||::||:|:..|.:||:
 Frog     1 MRFTTVDYIIFVLLLVLSSAIGLYYALSGGKQRTMQEFLLANRSMSFLPISLSLLATFQSAVAIL 65

  Fly    87 SIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVT 151
            .:|:|.|.:|..|.|:..:.::.:.|..:|.:||||...:::.|||||:||:|..|...|..|:.
 Frog    66 GVPSEIYRFGTEYWFLGCSYIIGLLIPAHIFIPVFYRLRLTSTYEYLELRFSKAVRICGTVTFIF 130

  Fly   152 NSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVA 216
            ...:.:.|.::.|:|||..|||.::....:.:..:|..||.|||:|||:||||:|..:|....:|
 Frog   131 QMVIYMGVVLYAPALAFNAVTGFSLWGAVLSMGLVCTLYTTLGGLKAVIWTDVIQTLVMFAGQLA 195

  Fly   217 VGVLGTIRSGGMFTVMERASDGGRF-NFDFGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRI 280
            |.::|||:.||...|...|::..:. ..::..||..|.:||...:|||||.....|:||:.|||.
 Frog   196 VIIVGTIKVGGFDQVWNIATENNKIAGVNWNPDPFERHSFWSLAIGGIFMMLSLYGVNQAQVQRY 260

  Fly   281 VSLPSYSHAKKSLIVSGLGFL----IISFFNTISGIIMFARYYGCDPMLAGL-VSKPDKMMPFFV 340
            :|    |..:|..|:|.....    ::.....::|::||| ||..:|..... :|.||:|:.:||
 Frog   261 LS----SRTEKEAILSCYAVFPCQQLVLALGCLTGLVMFA-YYKINPSAYPQDISVPDQMVLYFV 320

  Fly   341 QDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIRH-TEARANWAMKLIVVVM 404
            .||:..|.|:||:|::|:||.|||::|:..||||.|...|.|||.... ||::|.|..|.:.:..
 Frog   321 MDILKDLPGLPGLFVACLFSGALSTISSAFNSLATVTMQDLIKPHFPSLTESQATWLSKGLALGY 385

  Fly   405 GGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIVSVVAMVWII 469
            |..|:...::.....|:||..::|.|:..|.::|:|.||.|.|..|:..|::.:...:|...||
 Frog   386 GLLCLGMAYISSLMGSVLQAALSIFGMVGGPLLGLFCLGFFFPFTNSIGAMSGLAAGLVMAFWI- 449

  Fly   470 ANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDF-------------TPVTMKPPSGA 521
              |..:|.:.:......|             :..|.:..||             :|...|..||.
 Frog   450 --GIGSFVTRMPSVPPPP-------------LLNATSVPDFGNLTTTVMSTLLTSPTAKKSVSGL 499

  Fly   522 PVTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPFVRKFLSLP 586
            .           ..|.:|:.||....|..|.:..:.:|.:..|.:....:|:..      :|.||
 Frog   500 Q-----------KFYSLSYMWYSAHNSTTVVIVGLIVSLLTGPTKGRDIDPRTV------YLVLP 547

  Fly   587  586
             Frog   548  547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	175/553 (32%)
slc5a6	XP_031757499.1	SLC5-6-like_sbd	3..530	CDD:444915	176/558 (32%)