DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2187 and ChT

DIOPT Version :9

Sequence 1:	NP_001189331.1	Gene:	CG2187 / 43743	FlyBaseID:	FBgn0017448	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_650743.1	Gene:	ChT / 42245	FlyBaseID:	FBgn0038641	Length:	614	Species:	Drosophila melanogaster

Alignment Length:	524	Identity:	105/524 - (20%)
Similarity:	198/524 - (37%)	Gaps:	143/524 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GLTDYFVFVIMLGASAGIGVYFGFFSKSKN-TTEEYLRGGKKMQTLPIAISLVASQLSGIAIMSI 88
            |:....:|.:::   ..:|::.|...:|.| :.||.:..|:.:.......::.|:.:.|..|...
  Fly     6 GVVSIVLFYLLI---LVVGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGT 67

  Fly    89 PAESYTYG-------FNYIFVVLAMLVVIPILIYIIVPVFYENNVS-----NCYEYLEMRFNKRT 141
            ....||.|       |.|            .|..:...:|:.|.:.     ...:.|:..|.:|.
  Fly    68 AEAIYTSGLVWCQAPFGY------------ALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERM 120

  Fly   142 RQLVTFFFVTNSFLMLPVYMFIPSL----------------AFAQVTGMNIHLINVMVSS-ICIF 189
            ..|                :|:|:|                ..:.:..|: |..:|::|| |.||
  Fly   121 GGL----------------LFLPALCGEVFWAAGILAALGATLSVIIDMD-HRTSVILSSCIAIF 168

  Fly   190 YTMLGGIKAVVWTDVVQ------GAIMLL----SVVAVGVLGTIRSGGMFTVMERASDGGRFNFD 244
            ||:.||:.:|.:|||:|      |..|.:    |...||.|..:....:..|..:..   ....|
  Fly   169 YTLFGGLYSVAYTDVIQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVDWIGHVEPKKH---WLYID 230

  Fly   245 FGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTI 309
            :||    .:.|     ||| .|       |...||::|..:...|:....|:..|.::::....:
  Fly   231 YGL----LLVF-----GGI-PW-------QVYFQRVLSSKTAGRAQLLSYVAAAGCILMAIPPVL 278

  Fly   310 SGIIMFAR------YYGCDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSA 368
            .|.|..|.      |.|..|:   .|.:...::|..:|.:........|  :..|.:|.:||..:
  Fly   279 IGAIAKATPWNETDYKGPYPL---TVDETSMILPMVLQYLTPDFVSFFG--LGAVSAAVMSSADS 338

  Fly   369 TLNSLAGVVYFDYIKP--RIRHTEARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGI 431
            ::.|.|.:...:..|.  |.:.:|....|.|::.::|:|               ||.|::.:|
  Fly   339 SVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVG---------------ILATIMALT-- 386

  Fly   432 NTGAVVGVF----------------LLGMFVPRCNAKTAVTSIIVSVVAMVWIIANGQMNF-KSG 479
             ..::.|::                ::..|...||...::::.|   ||:...::.|:... .:.
  Fly   387 -IPSIYGLWSMCSDLVYVILFPQLLMVVHFKKHCNTYGSLSAYI---VALAIRLSGGEAILGLAP 447

  Fly   480 LIKY 483
            ||||
  Fly   448 LIKY 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	104/522 (20%)
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	104/523 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448238
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740