Protein Alignment CG2187 and slc5a8.1

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001351880.1
• Gene: slc5a8.1 / 394505
• XenbaseID: XB-GENE-479634
• Length: 620
• Species: Xenopus tropicalis
• Alignment Length: 635
• Identity: 196/635 - (30%)
• Similarity: 315/635 - (49%)
• Gaps: 70/635 - (11%)

  Fly    24 FGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISLVASQLSGIAIMSI 88
            |.:.||.||.:||..||.||:|:.|....:.|::::|.||:.|..:|:|:||.||.:|.:.::..
 Frog    10 FTVWDYVVFALMLLISAVIGIYYAFAGGGQKTSKDFLMGGRSMTAVPVALSLTASFMSAVTVLGT 74

  Fly    89 PAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNS 153
            |||.|.:|..:........:|:.|...:.:||||...:::.|||||:||||..|.|.|..|:..:
 Frog    75 PAEVYRFGSMFSIFAFTYAIVVVISSEVFLPVFYRLGITSTYEYLELRFNKFVRLLGTILFIIQT 139

  Fly   154 FLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVG 218
            .|...:.::.|:||..||||.::....|....:|.||..:||:||||||||.|..||:....:|.
 Frog   140 VLYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTMGGLKAVVWTDVFQVGIMVAGFSSVI 204

  Fly   219 VLGTIRSGGMFTVMERASDGGRFNF-DFGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVS 282
            :...:..||:..::..:..|.|.|| ||..:|..|.:||...:||.|.|||..|:|||.|||.::
 Frog   205 IRAVVVQGGIGPILNDSYYGDRLNFWDFTPNPLQRHSFWTIVVGGTFTWTGIYGVNQSQVQRYIA 269

  Fly   283 LPSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCDPMLAGLVSKPDKMMPFFVQDIMGHL 347
            ..:...||.||.::.||...|.....:||:.|::.|..|||..|..||.||::||:...||:...
 Frog   270 CKTRFQAKLSLYINLLGLWAILACAVLSGLAMYSIYKDCDPWTAQFVSAPDQLMPYLSLDILRDY 334

  Fly   348 AGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIRH-TEARANWAMKLIVVVMGGYCILG 411
            .|:||:|:||.:|..||::|:::|:||.|...|.|||..|. :|.:.:|..|...::.|..||..
 Frog   335 PGLPGLFVSCAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSETKMSWISKGTSLIYGAICIAM 399

  Fly   412 GFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIVSVVAMVWIIANGQM-- 474
            ..:......:||..::|.|:..|.::|:|.||:..|..|:..||..::......:|:....|:
 Frog   400 AGLASLMGGLLQAALSIFGMVGGPLLGLFALGIIFPFVNSLGAVIGLLSGFAISLWVGIGSQIYP 464

  Fly   475 -NFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSGAPVTTAF------HSDRD 532
             ...|.|.|    |.||:.|.....        ::::|...|      |:.|..      ..:..
 Frog   465 PTASSSLPK----PLSLEGCNFTSF--------ESNWTTTVM------PMMTTLIPEVSSRPELA 511

  Fly   533 FSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPFVRKFLSLPVTDQDL----- 592
            .|.|.:|:.::..||:.:..:..:..|.:   ....|||..      |.||   :|.||.
 Frog   512 DSWYSLSYLYFSTLGTIVAVVVGVIASLL---SGGLKQNVN------RDFL---LTSQDFSYLNV 564

  Fly   593 -----------EEVPLRGSKVAATP-------------DLRIEPTEKEKQ 618
                       |:|.:...|:.:|.             .:.:..|||:::
 Frog   565 LFSNCKKKGQEEKVEVLNWKMRSTDTDMDQGTDNPAFNHMEMSSTEKKEK 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	179/544 (33%)
slc5a8.1	NP_001351880.1	SLC5sbd_SMCT1	7..547	CDD:271402	181/557 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.020