Protein Alignment CG2187 and Slc5a9

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001382057.1
• Gene: Slc5a9 / 366441
• RGDID: 1311383
• Length: 688
• Species: Rattus norvegicus
• Alignment Length: 686
• Identity: 161/686 - (23%)
• Similarity: 266/686 - (38%)
• Gaps: 159/686 - (23%)

  Fly     6 TTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLP 70
            ||...:.|.||..:.|: ..:..|||||:.:|..:.|       ..|:.|...|...|:.|...|
  Rat    21 TTHQALGSGVSLHTYDI-VVVVIYFVFVLAVGIWSSI-------RASRGTIGGYFLAGRSMTWWP 77

  Fly    71 IAISLVASQLS-----GIAIMSIPAESYTYGF--NYIFVVLAMLVVIPILIYIIVPVFYENNVSN 128
            |..||::|.:.     |:|...........||  |..|::||       |.:|.|||:....|..
  Rat    78 IGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATFLLLA-------LGWIFVPVYIAAGVVT 135

  Fly   129 CYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIP--------SLAFAQVTGMNIHLINVMVSS 185
            ..:||:.||..:..|      |..|.|.|.:|:|..        :|......|.|::|..|::..
  Rat   136 MPQYLKKRFGGQRIQ------VYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTVILLV 194

  Fly   186 ICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMER---------------- 234
            :...||:.||:.||::||.:|..||:...:.:..|| .|..|.:..:::
  Rat   195 VTAVYTIAGGLTAVIYTDALQTVIMVGGALVLMFLG-FREVGWYPGLQQLYRQSIPNVTVPNTTC 258

  Fly   235 ---ASDGGRFNFDFGLDPRIRMTFWGATMGGIFMWTGHI-GL----------NQSCVQRIVSLPS 285
               .||.    |....||          :.|...|.|.| ||          :|..|||.:|..|
  Rat   259 HLPRSDA----FHMLRDP----------VNGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKS 309

  Fly   286 YSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYG---------CDPMLAGLVSKPDKMMPFFVQ 341
            .||||...::.|...::..||..:.|:|..|.|..         |..:....|...:...|..|.
  Rat   310 LSHAKGGSVLGGYLKILPMFFIVMPGMISRALYPDEVACVDPDICQRVCGARVGCSNIAYPKLVM 374

  Fly   342 DIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIRH--TEARANWAMKLIVVVM 404
            .:|.  .|:.|:.|:.:.:|.:|||::..||.:.:...| :..|:|.  :|.......:|.||.:
  Rat   375 ALMP--VGLRGLMIAVIMAALMSSLTSIFNSSSTLFAID-VWQRVRRQASEQELMVVGRLFVVFL 436

  Fly   405 GGYCILGGFMVQNFNS--ILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIVSVVAMVW 467
            ....||...::|:.||  :...:.:||......:..:|||.:|..|.....|...::..:|.
  Rat   437 VLISILWIPIIQSSNSGQLFDYIQSITSYLAPPITALFLLAIFCKRVTEPGAFWGLMFGLVV--- 498

  Fly   468 IIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSGAPVTTAFHSDRD 532
                       |:::. :|..|..          |.|..:.|..|..:|
  Rat   499 -----------GILRM-ILEFSYS----------APACGEKDRRPAVLK---------------- 525

  Fly   533 FSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLY----SPF--VRKFLSLPVTDQD 591
                |..:.::.:|...|..:..:.:|:...|..:||.....:    .|.  ::|.:|:.|.:.:
  Rat   526 ----DFHYLYFALLLCGLTAIIIVIISFFTEPIPDEKLARLTWWTRSCPISELQKKVSVSVNNTE 586

  Fly   592 LEEVP-LRGSKVAATPDLRIEPT---EKEKQTVTEP 623
            .:..| |.|..|       :|.|   |:|..|.:||
  Rat   587 SDNSPALAGRPV-------MEGTAGDEEEANTTSEP 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	137/591 (23%)
Slc5a9	NP_001382057.1	SLC5-6-like_sbd	48..688	CDD:444915	150/658 (23%)