Protein Alignment CG2187 and SLC5A11

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_609192.1
• Gene: SLC5A11 / 34117
• FlyBaseID: FBgn0031998
• Length: 600
• Species: Drosophila melanogaster
• Alignment Length: 602
• Identity: 195/602 - (32%)
• Similarity: 318/602 - (52%)
• Gaps: 53/602 - (8%)

  Fly    11 MASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSK-----------NTT-------- 56
            |.:......::.|||..||.||:.|:..|...|:|||...|||           .||
  Fly     1 MEAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDF 65

  Fly    57 -----EEYLRGGKKMQTLPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYI 116
                 .|||.|.:.::..|:|:||:||.:||:.|:...:|.|.||..|.|:.:|:::....:.|:
  Fly    66 GSEKMSEYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYV 130

  Fly   117 IVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINV 181
            .:|||....|.:.||||||||:...|.:.:|.|:.:..|.||..:::|::|..||:|:|:|:|.|
  Fly   131 YIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAV 195

  Fly   182 MVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFNF-DF 245
            ::..:|:|||.:|||||||.||..|..:|.|||:||.:|.|:.:.|:..:.:.|:.|||..| :.
  Fly   196 VIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNT 260

  Fly   246 GLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTIS 310
            ...|.:|.|.|...:||...||....:||:.|||.:||||...|:.|:.:..:|  :.:|.:...
  Fly   261 NPSPYVRHTVWSVLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIG--VAAFVSVCC 323

  Fly   311 --GIIMFARYYGCDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSL 373
              |::::..|..|||:.|||::..|:::|.||...:||:.||.|:||:.:|.|||||||..|||.
  Fly   324 YVGLLIYEMYKDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNST 388

  Fly   374 AGVVYFDYIKP--RIRHTEARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAV 436
            :.|:..|.::.  :::.:|..:...:|..|:|:|...:...|:::..:.||....::|.|..|..
  Fly   389 SLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTT 453

  Fly   437 VGVFLLGMFVPRCNAKTAVTSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMI 501
            .|:|.|||.||..|........|.|.:...||....|....:|.:..:.||.|::.|...
  Fly   454 FGLFTLGMLVPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGN----- 513

  Fly   502 AEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDE 566
                       ||::.      ......::.|.||.:|::|...:|.|.|.:....:|.:.:|..
  Fly   514 -----------VTLRE------NIWVDEEQVFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTN 561

  Fly   567 NEKQNPKLYSPFVRKFL 583
            .:..:|.|.||.:.:||
  Fly   562 MKTLDPDLISPVIHRFL 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	184/562 (33%)
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	184/562 (33%)