Protein Alignment CG2187 and Gm5134

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_006513854.1
• Gene: Gm5134 / 333669
• MGIID: 3646667
• Length: 695
• Species: Mus musculus
• Alignment Length: 535
• Identity: 112/535 - (20%)
• Similarity: 215/535 - (40%)
• Gaps: 121/535 - (22%)

  Fly     5 TTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTL 69
            |...:|:..::.|.:..|  .:|.|.:.|:.:|       .:...|.|:.|.:::...|:.:...
Mouse    11 TWNQSTLGLSLHSTTDTL--VMTFYLLLVVCVG-------LWALLSHSRGTVKDFFLAGQNLAWW 66

  Fly    70 PIAISLVASQL--------------SGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPV 120
            .:.||:.:|.:              ||||:.::.       :|.||::.       :|.:|.||:
Mouse    67 LMGISIYSSNIGSGHYMALAGIGAASGIAVGALE-------WNSIFMLF-------LLGWIFVPI 117

  Fly   121 FYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMF--------IPSLAFAQVTGMNIH 177
            :.:..|....|||:.||.....||   ||   :|:.|.||:|        ..::....|...:|:
Mouse   118 YSKAEVVTLPEYLKKRFGSLRIQL---FF---TFIFLIVYIFSRISMEIGFGAMFLKMVWDTDIY 176

  Fly   178 LINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLL--------SVVAVGVLGTIRSGGMFTVMER 234
            ...:.|.:|...||:.||:..|.:.:.:|..||:|        :...||....:.|..|..:..:
Mouse   177 QTMLTVLTIIGMYTITGGLATVAYVESLQAGIMILGSALLMGYAFYEVGGYPKLVSKYMEAIPSK 241

  Fly   235 ASDGGRFNFDFGLDPRIRMT------FWGATMGGIFMWTG------HIGLNQSCVQRIVSLPSYS 287
            ...|     ::...|...:.      .:.:.:.|...|.|      .:.|...|..: ||:..:.
Mouse   242 TQQG-----NWTAQPECYLPRQDAFHIFRSCVSGDIPWPGLILGATTVSLFYGCADQ-VSVQRFL 300

  Fly   288 HAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCDPMLAGLVSK---PDKM-------------- 335
            ..|..|.:.| |.|:..:...:...:|         ::.|::|:   ||::
Mouse   301 AGKSRLHMEG-GCLLCGYLKLLPMFLM---------VMPGMISRILYPDQVACVVPSECQKFCGR 355

  Fly   336 --------MPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVV---YFDYIKPRIRHT 389
                    .|..|..:|.|  |:.|..:|.|.::.:|||::..||.:.:.   .:.:|:|..  |
Mouse   356 GTGCSALAYPVLVLGVMPH--GLQGFMLSTVCASLMSSLTSIFNSSSALFTLNIYTWIRPTA--T 416

  Fly   390 EARANWAMKLIVVVMGGYCILGGFMVQNF-NSIL-QTVVTITGINTGAVVGVFLLGMFVPRCNAK 452
            |.....|.:..|:::....|:...:::.. |.|| :.:..:....|.::..||||.:|..|.|.:
Mouse   417 EKELMIAGRFFVIILLAVTIVWIPIIEMAPNEILFEYMQVLKSCLTPSMTAVFLLAVFCKRVNEQ 481

  Fly   453 TAVTSIIVSVVAMVW 467
            .|...:||.....|:
Mouse   482 GAFWGLIVGTTIGVF 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	108/513 (21%)
Gm5134	XP_006513854.1	SLC5-6-like_sbd	26..695	CDD:444915	109/520 (21%)