Protein Alignment CG2187 and Slc5a6

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_808538.1
• Gene: Slc5a6 / 330064
• MGIID: 2660847
• Length: 634
• Species: Mus musculus
• Alignment Length: 632
• Identity: 187/632 - (29%)
• Similarity: 308/632 - (48%)
• Gaps: 76/632 - (12%)

  Fly     1 MSTTTT-----TTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYL 60
            ||..:|     ||:..:.|:|:      |.:.||.||.::|..|..||:|........:|..|.|
Mouse     1 MSVASTAAPFHTTSGSSGAIST------FSVVDYVVFGLLLVLSLVIGLYHACRGWGHHTVGELL 59

  Fly    61 RGGKKMQTLPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENN 125
            ...:||..||:|:||:|:..|.:||:..|||.:.:|..|.|:..:..:.:.|..:|.:||||..:
Mouse    60 MADRKMGCLPVALSLLATFQSAVAILGAPAEIFRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLH 124

  Fly   126 VSNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFY 190
            :::.|||||:||||..|...|..|:....:.:.|.::.||||...|||.::.|..:.:..:|..|
Mouse   125 LTSAYEYLELRFNKAVRICGTVTFIFQMVIYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIY 189

  Fly   191 TMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFN-FDFGLDPRIRMT 254
            |.|||:|||:||||.|..:|.|..:.|.::|..|.||:..|....|..|..: .:...||.:|.|
Mouse   190 TALGGLKAVIWTDVFQTLVMFLGQLVVIIVGAARVGGLGHVWNVTSQHGLISGINLDPDPFVRHT 254

  Fly   255 FWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFL----IISFFNTISGIIMF 315
            ||....||:||.....|:||:.|||.:|    ||::::.::|.....    :....:.:.|::||
Mouse   255 FWTLAFGGVFMMLSLYGVNQAQVQRYLS----SHSERAAVLSCYAVFPCQQVALCMSCLIGLVMF 315

  Fly   316 ARY--YGCDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVY 378
            |.|  |...|.|.  .:.||:::.:||.|::..:.|:||:|::|:||.:||::|:..||||.|..
Mouse   316 AYYNMYSMSPELK--QAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTM 378

  Fly   379 FDYIKPRI-RHTEARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFLL 442
            .|.|:|.. :.||.||....:.:....|..|:...::..:..|:||..::|.|:..|.::|:|.|
Mouse   379 EDLIQPWFPQLTETRAIMLSRGLAFAYGLVCLGMAYISSHLGSVLQAALSIFGMVGGPLLGLFCL 443

  Fly   443 GMFVPRCNAKTAVTSIIVSVVAMVWI------------IANGQMNFKSGLIKYEVLPNSLDQCEA 495
            |:|.|..|...|:..::..:....||            :|...:|..|..:...|...::
Mouse   444 GLFFPCANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAVAPPPLNGSSSFLPANVTVAAV----- 503

  Fly   496 RGLYMIAEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSY 560
                        |...|.|:..|:|..           ..|.:|:.||....|..|.:..:.:|.
Mouse   504 ------------TTVMPSTLSKPTGLQ-----------HFYSLSYLWYSAHNSTTVIVVGLIVSL 545

  Fly   561 IWRPDENEKQNPKLYSPFVRKFLS-LPVT----------DQDLEEVP 596
            :.........||....|.:.|.|: ||::          .||:..:|
Mouse   546 LTGGMRGRSLNPGTIYPVLPKLLALLPLSCQKRLCWRSHSQDIPVIP 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	169/553 (31%)
Slc5a6	NP_808538.1	SLC5-6-like_sbd	23..548	CDD:444915	170/558 (30%)