Protein Alignment CG2187 and Slc5a4b

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_008771154.1
• Gene: Slc5a4b / 294342
• RGDID: 1309867
• Length: 660
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 136/619 - (21%)
• Similarity: 245/619 - (39%)
• Gaps: 128/619 - (20%)

  Fly     1 MSTTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKK 65
            :|.:|...|.....||...|:    ..|..|.||.......:|:: .....::.|...:...|:.
  Rat     5 LSPSTAPRTEEPPEVSERIQN----AADISVIVIYFLVVLAVGLW-SMVRSNRGTIGGFFLAGRD 64

  Fly    66 MQTLPIAISLVASQL--------------SGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYI 116
            :...|:..||.||.:              |||||.::.       :|.:.:||       :|.::
  Rat    65 VSWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVE-------WNALLMVL-------VLGWV 115

  Fly   117 IVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVY----MFIPSLAFAQVTGMNIH 177
            .||::.:..|:...|||..||..:..|:  :..|.:.|:|:.:.    :|..::......|:|::
  Rat   116 FVPIYIKAGVTTMPEYLRKRFGGKRLQI--YLSVLSLFIMVAIQTSSTIFSGAIFIQLALGLNLY 178

  Fly   178 LINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLL-SVVAVG------------------VLGTI 223
            |...::.:|..|||:.||:.:|::||.||..|||: |::.:|                  .:.::
  Rat   179 LAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLVGSLILMGFAFAEVGGYESFTEKYMNAIPSV 243

  Fly   224 RSGGMFTVMERASDGGRFNFDFGLDPRIRMTFW-----GATMGGIFMWTGHIGLNQSCVQRIVSL 283
            ..|...|:..:.......:|....||......|     |.|:..|:.|..    :|..|||.:..
  Rat   244 VEGDNLTISPKCYTPQPDSFHIFRDPINGDIPWPGLIFGMTILAIWYWCA----DQVMVQRCLCG 304

  Fly   284 PSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYG---------CDPMLAGLVSKPDKMMPFF 339
            .:.||.|.:.|:.|...|:..|...:.|:|....|..         |.......|...:...|..
  Rat   305 KNMSHVKAACIMCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECVKQCGTAVGCTNYAYPTL 369

  Fly   340 VQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFD-YIKPRIRHTEARANWAMKLIVVV 403
            |.::|..  |:.|:.:|.:.::.:|||::..||.:.:...| |.|.|.:.:|.....|.::..:|
  Rat   370 VLELMPD--GLRGLMLSVMLASLMSSLTSIFNSASTLFTMDLYTKIRKKASERELMVAGRVFGIV 432

  Fly   404 MGGYCILGGFMVQ-NFNSILQTVVTITGINTGAVVG-VFLLGMFVPRCNAKTAVTSIIVSVVAMV 466
            :....||...::| :.|..|...::......|..|| ||||.:|..|.|.:.|...::|.:|.
  Rat   433 LIVISILWVPLIQASQNGQLFHYISSFSSYIGPPVGAVFLLAIFCKRVNEQGAFWGLMVGLVI-- 495

  Fly   467 WIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSGAP-VTTAFHSD 530
                        |||:                 ||.|.|..|.    :...||..| :....|
  Rat   496 ------------GLIR-----------------MITEFIYGTG----SCLEPSNCPRIICGVH-- 525

  Fly   531 RDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRP 564
                     :.::.::...:..|..:.:|::..|
  Rat   526 ---------YMYFAIILFFVSILVILGVSFLTEP 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	129/588 (22%)
Slc5a4b	XP_008771154.1	SLC5-6-like_sbd	27..660	CDD:444915	130/593 (22%)