Protein Alignment CG2187 and Slc5a4

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001099853.1
• Gene: Slc5a4 / 294341
• RGDID: 1306923
• Length: 671
• Species: Rattus norvegicus
• Alignment Length: 726
• Identity: 156/726 - (21%)
• Similarity: 269/726 - (37%)
• Gaps: 211/726 - (29%)

  Fly     2 STTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKM 66
            ||.:.:|:|.:|.:||.|.::. ...|..|.||.......:||: .....:::|...:...|:.|
  Rat    14 STASVSTSTGSSELSSLSDNIN-NPADISVIVIYFVVVMAVGVW-AMVKTNRSTVGGFFLAGRSM 76

  Fly    67 QTLPIAISLVASQL--------------SGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYII 117
            ...|:..||.||.:              :|||:.:..:.|:           |:|:|   |.:..
  Rat    77 TWWPMGASLFASNIGSGHFVGLAGTGAATGIAVTAFESHSF-----------ALLLV---LGWFF 127

  Fly   118 VPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSF----LMLPVYMFIPSLAFAQVTGMNIHL 178
            ||::.:..|....|||..||..:..|:  :..|.:.|    |.:...:|..::......|::::|
  Rat   128 VPIYIKAGVMTMPEYLRKRFGGKRLQI--YLSVLSLFICVILTISADIFSGAIFIKLALGLDLYL 190

  Fly   179 INVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMER-------AS 236
            ...::.:|...:|:.||:.:|::||.:|..|||:....:.:...:..||..:..|:       ..
  Rat   191 AIFILLAITAVFTITGGLASVIYTDTLQAIIMLVGSFILMIYAFVEVGGYESFTEKYMNAIPSVV 255

  Fly   237 DGGRFNFD---FGLDPRIRMTFWGATMGGIFMWTG-----------HIGLNQSCVQRIVSLPSYS 287
            :|......   :...|.....|..|..|.| .|.|           :..:||..|||.:...:.|
  Rat   256 EGDNLTISPKCYTPQPDSFHIFRDAVTGDI-PWPGTAFGMPITALWYWCINQVIVQRCLCGKNMS 319

  Fly   288 HAKKSLIVSGLGFLIISFFNTISGIIMFARY-------------------YGCD----PMLAGLV 329
            |.|.:.||.|...|:..||..:.|:|....|                   .||.    |||.
  Rat   320 HVKAACIVCGYLKLLPIFFMVMPGMISRILYTDMVACVVPSECVKQCGVDVGCTNYAYPMLV--- 381

  Fly   330 SKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFD-YIKPRIRHTEARA 393
               .|:||.          |:.|:.:|.:.::.:|||::..||.:.:...| |.|.|.:.:|...
  Rat   382 ---LKLMPM----------GLRGLMLSVMLASLMSSLTSIFNSASTLFTMDLYTKIRKKASEREL 433

  Fly   394 NWAMKLIVVVMGGYCIL---------GGFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRC 449
            ..|.:|.|.|:....||         ||       .::.....|:......:..|||:.:|..|.
  Rat   434 LIAGRLFVSVLIVTSILWVPIVEVSQGG-------QLIHYTEAISSYLGPPIAAVFLVAIFCKRV 491

  Fly   450 NAKTAVTSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVT 514
            |.:.|...::|.:|.              |||:                 ||||....|.    :
  Rat   492 NEQGAFWGLMVGLVL--------------GLIR-----------------MIAEFSYGTG----S 521

  Fly   515 MKPPSGAPVTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRP--------------- 564
            ...||..|..          :..:.:.:|.::...:..|..:.:||:.:|
  Rat   522 CLAPSSCPKV----------ICGVHYLYYAIILFFVSILVILGVSYLTKPIPDVHLYRLCWSLRN 576

  Fly   565 -------------DENEKQNPKLYSPFVRKFLSLPVTDQDLEEVPLRGSKVAATPDL-----RIE 611
                         :|||..               ..|::|..|.| ||. :..|.||     |.|
  Rat   577 SEEERIDLDAEDREENEAD---------------ARTEEDQTEKP-RGC-LKKTYDLCCGLQRAE 624

  Fly   612 P--TEKEKQTV 620
            |  |::|::.:
  Rat   625 PKLTKEEEEAL 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	129/605 (21%)
Slc5a4	NP_001099853.1	SLC5-6-like_sbd	38..671	CDD:444915	148/701 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	583..604		5/35 (14%)