Protein Alignment CG2187 and Slc5a1

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_062784.3
• Gene: Slc5a1 / 20537
• MGIID: 107678
• Length: 665
• Species: Mus musculus
• Alignment Length: 530
• Identity: 133/530 - (25%)
• Similarity: 217/530 - (40%)
• Gaps: 84/530 - (15%)

  Fly     2 STTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKM 66
            |:|.:...|...|...:.:.:| ...|..|.||.......:|:: ..||.::.|...:...|:.|
Mouse     3 SSTLSPAVTATDAPIPSYERIR-NAADISVIVIYFVVVMAVGLW-AMFSTNRGTVGGFFLAGRSM 65

  Fly    67 QTLPIAISLVASQLS-----GIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNV 126
            ...||..||.||.:.     |:|.....|.....||.:     ..||::.:|.:|.||::.:..|
Mouse    66 VWWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEW-----NALVLVVVLGWIFVPIYIKAGV 125

  Fly   127 SNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLA-------FAQVT-GMNIHLINVMV 183
            ....|||..||..:..|:..      |.|.|.:|:|....|       |..:. |::|:|...::
Mouse   126 VTMPEYLRKRFGGKRIQIYL------SVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFIL 184

  Fly   184 SSICIFYTMLGGIKAVVWTDVVQGAIMLL-SVVAVG------------------VLGTIRSGGMF 229
            .:|...||:.||:.||::||.:|.||||: |.:..|                  .:.|..|.|.|
Mouse   185 LAITALYTITGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNF 249

  Fly   230 TVMERASDGGRFNFDFGLDPRIRMTFWGATMGGIFMWTGHI-GL----------NQSCVQRIVSL 283
            |..|........:|....||          :.|...|.|.| ||          :|..|||.:|.
Mouse   250 TAKEECYTPRADSFHIFRDP----------ITGDMPWPGLIFGLAILALWYWCTDQVIVQRCLSA 304

  Fly   284 PSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARY---------YGCDPMLAGLVSKPDKMMPFF 339
            .:.||.|....:.|...|:..|...:.|:|....|         ..|.......|...:...|..
Mouse   305 KNMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTL 369

  Fly   340 VQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFD-YIKPRIRHTEARANWAMKLIVVV 403
            |.::|.:  |:.|:.:|.:.::.:|||::..||.:.:...| |.|.|.:.:|.....|.:|.::|
Mouse   370 VVELMPN--GLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKASEKELMIAGRLFILV 432

  Fly   404 MGGYCILGGFMVQNFNS--ILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTA----VTSIIVSV 462
            :.|..|....:||:..|  :...:.:||......:..||||.:|..|.|.:.|    :...::.:
Mouse   433 LIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGFLIGI 497

  Fly   463 VAMVWIIANG 472
            ..|:...|.|
Mouse   498 SRMITEFAYG 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	128/505 (25%)
Slc5a1	NP_062784.3	SLC5-6-like_sbd	27..665	CDD:444915	128/505 (25%)