Protein Alignment CG2187 and smvt-1

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_001360058.2
• Gene: smvt-1 / 186132
• WormBaseID: WBGene00018716
• Length: 565
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 150/595 - (25%)
• Similarity: 277/595 - (46%)
• Gaps: 78/595 - (13%)

  Fly    32 FVIMLGASAGIGVYFGFFSKSKNTTEEY----LRGGKKMQTLPIAISLVASQLSGIAIMSIPAES 92
            :|.:|.....|..| ||....|...||.    ...|.::......:|:.:..:|.|:::..|||.
 Worm     6 YVTLLTCLISISAY-GFIKSRKTENEEQSVHATMVGSRVSVWSATLSVCSGFISSISLLGFPAEI 69

  Fly    93 YTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSFLML 157
            |..|...::.....::..||:.::.:||.|...::..|||.|.||:.:.|.:.|..|.....|..
 Worm    70 YYQGGMMLWFAPMYVISFPIVAFVFLPVLYRLKLTTIYEYFERRFDYKCRFVTTSLFCVQMILYN 134

  Fly   158 PVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGT 222
            .|.::.||||.|.:|.:.|.:..::.:.:..||..:||:||.:.|..:|..::.|::..: :..:
 Worm   135 SVALYAPSLAIASITNIPITVSILITAVLSAFYISVGGVKAGIHTSAIQMLLIFLTMTFI-ISIS 198

  Fly   223 IRSGGMFTVMERASDGGRFNF-DFGLDPRIRMTFWGATMGGIFMWTGHI----GLNQSCVQRIVS 282
            :|...:..|......|.||.. ||.::|.||.:.|...:||    ||:|    ..||..:||.::
 Worm   199 LREMSIHDVYTSVVHGKRFILNDFRINPTIRHSVWSLLIGG----TGNILALFAANQLSIQRYMA 259

  Fly   283 LPSYSHAKKSLIVSGL--GFLIISFFNTISGIIMFARYYGCDPMLAGLVSKPDKMMPFFVQDIMG 345
            :.:...|:|.::::.:  ..:::|:.:.  |.:::|.|..|.|.    :...::::|.||.|:..
 Worm   260 MDTLKSAQKVVLLNIVCNTIILVSYVSV--GFLIYAHYKDCHPQ----IGNANELLPRFVMDVTS 318

  Fly   346 HLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFD----YIKPR----IRHTEARANWAMKLIVV 402
            ...|..|:|.:.|:||.:|:|||:..:::.:|..|    |.:.|    :|:.:.:.  ||:::.:
 Worm   319 KYPGSVGLFAAAVYSAGISTLSASFTAVSSIVINDVWKVYRERRKMAPLRNDQVQN--AMRILPI 381

  Fly   403 VMGGYCILGGFMVQNFNS-ILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIVSVVAMV 466
            |:....|...|:.....| |||....:.|...|.|:|.|::|:||||...|.|:..:|.|::...
 Worm   382 VLSFISIFVAFLCSMLQSIILQVSFIVFGAGGGPVLGSFVVGLFVPRVKEKAALVGLIGSIIVCF 446

  Fly   467 WIIANGQMNFKSGLIKYEVLPNSLDQCEARGL-YMIAEAINKTDFTPVTMKPPSGAPVTTAFHSD 530
                  .::..|.|:|.:.:...|.||..:.| |.....|.....||:            .|..:
 Worm   447 ------SISIGSVLVKVKPVALELGQCSNQTLTYFDESFIGAVTSTPL------------VFGLE 493

  Fly   531 RDFSLYDISFYWYKVLG-----------SALVFLCAIPLSYIWRPDENEKQNPKL-YSPFVRKFL 583
            |.|:   ||:.:|.::.           ..|..||::..:::  |..:|..:|.| ||...|
 Worm   494 RIFA---ISYQYYSIIAVVTNVALSIVMQKLFELCSLTANHL--PVSHELVSPLLTYSSSKR--- 550

  Fly   584 SLPVTDQDLE 593
                 |.:||
 Worm   551 -----DPELE 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	140/560 (25%)
smvt-1	NP_001360058.2	SLC5sbd_NIS-SMVT	5..521	CDD:271383	137/549 (25%)