Protein Alignment CG2187 and cho-1

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_502539.1
• Gene: cho-1 / 178274
• WormBaseID: WBGene00000501
• Length: 576
• Species: Caenorhabditis elegans
• Alignment Length: 650
• Identity: 124/650 - (19%)
• Similarity: 217/650 - (33%)
• Gaps: 233/650 - (35%)

  Fly    30 FVFVIMLGASAGIGVYFGFFSKSKN--------TTEEYLRGGKKMQTLPIAISLVASQLSGIAIM 86
            |.:|::|    .:|::.|..|||..        .|||.:..|:.:.||....::.|:.:.|..|.
 Worm    12 FFYVLIL----VVGIWAGRKSKSSKELESEAGAATEEVMLAGRNIGTLVGIFTMTATWVGGAYIN 72

  Fly    87 SIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFY----------------ENNVSNCYEYLEM 135
            ......|..|                |:....||.|                |.......:..:.
 Worm    73 GTAEALYNGG----------------LLGCQAPVGYAISLVMGGLLFAKKMREEGYITMLDPFQH 121

  Fly   136 RFNKRTRQLVTFFFVTNSFLMLPVYMFIPSL----------------AFAQVTGMNIHLINVMVS 184
            ::.:|...|                |::|:|                ..:.:.|::::....:.:
 Worm   122 KYGQRIGGL----------------MYVPALLGETFWTAAILSALGATLSVILGIDMNASVTLSA 170

  Fly   185 SICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVG----VLGTIRSGGMFTVMERASD-----GGR 240
            .|.:|||..||..||.:|||||     |..:.||    |...:...|...:...|.|     ||.
 Worm   171 CIAVFYTFTGGYYAVAYTDVVQ-----LFCIFVGLWVCVPAAMVHDGAKDISRNAGDWIGEIGGF 230

  Fly   241 FNFDFGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISF 305
            ......:|..:.:.|     ||| .|       |...||::|..:...|:....|:|:|.::::.
 Worm   231 KETSLWIDCMLLLVF-----GGI-PW-------QVYFQRVLSSKTAHGAQTLSFVAGVGCILMAI 282

  Fly   306 FNTISGIIMFARYYGCDPMLAGLVSK----------------------PDK---MMPFFVQDIMG 345
                            .|.|.|.:::                      |||   ::|...|.:..
 Worm   283 ----------------PPALIGAIARNTDWRMTDYSPWNNGTKVESIPPDKRNMVVPLVFQYLTP 331

  Fly   346 HLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIR-H-TEARANWAMKLIVVVMGGYC 408
            ......|  :..|.:|.:||..:::.|.|.:...:..|..|| | :|......|::.::.:|
 Worm   332 RWVAFIG--LGAVSAAVMSSADSSVLSAASMFAHNIWKLTIRPHASEKEVIIVMRIAIICVG--- 391

  Fly   409 ILGGFMVQNFNSI------------------LQTVVTITGINT-GAVVGVFLLGMFVPRCNAKTA 454
            |:...|.....||                  |..||.:...|| |::.| :.:|:.:.....:..
 Worm   392 IMATIMALTIQSIYGLWYLCADLVYVILFPQLLCVVYMPRSNTYGSLAG-YAVGLVLRLIGGEPL 455

  Fly   455 V---------------------TSIIVSVVAMVWIIA-NGQMNFKSGLIKYE------------- 484
            |                     |:.::|.:|.::|:: ..:..||||.:..|
 Worm   456 VSLPAFFHYPMYTDGVQYFPFRTTAMLSSMATIYIVSIQSEKLFKSGRLSPEWDVMGCVVNIPID 520

  Fly   485 --VLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSGAPV-----------TTAFHSDRDFSLY 536
              .||:.:      ...:.:|.:|        ||.|:|.|.           .|..|...|.|.|
 Worm   521 HVPLPSDV------SFAVSSETLN--------MKAPNGTPAPVHPNQQPSDENTLLHPYSDQSYY 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	123/649 (19%)
cho-1	NP_502539.1	SLC5sbd_CHT	7..492	CDD:271368	105/555 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810