Protein Alignment CG2187 and Slc5a6

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: NP_570102.1
• Gene: Slc5a6 / 170551
• RGDID: 69648
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 188/610 - (30%)
• Similarity: 300/610 - (49%)
• Gaps: 64/610 - (10%)

  Fly     2 STTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKM 66
            |.||:.|..:.|.         |.:.||.||.::|..|..||:|.......::|..|.|...:||
  Rat    10 SYTTSDTNRVIST---------FSVVDYVVFGLLLVLSLVIGLYHACRGWGRHTVGELLMADRKM 65

  Fly    67 QTLPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYE 131
            ..||:|:||:|:..|.:||:..|||.|.:|..|.|:..:..:.:.|..:|.:||||..::::.||
  Rat    66 GCLPVALSLLATFQSAVAILGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAYE 130

  Fly   132 YLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGI 196
            |||:||||..|...|..|:....:.:.|.::.||||...|||.::.|..:.:..:|..||.|||:
  Rat   131 YLELRFNKAVRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGL 195

  Fly   197 KAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFN-FDFGLDPRIRMTFWGATM 260
            |||:||||.|..||.|..:.|.::|..:.||:..|...||..|..: .:...||.:|.|||....
  Rat   196 KAVIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHGLISGIELDPDPFVRHTFWTLAF 260

  Fly   261 GGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFL----IISFFNTISGIIMFARY--Y 319
            ||:||.....|:||:.|||.:|    ||::|:.::|.....    :....:.:.|::|||.|  |
  Rat   261 GGVFMMLSLYGVNQAQVQRYLS----SHSEKAAVLSCYAVFPCQQVALCMSCLIGLVMFAYYKKY 321

  Fly   320 GCDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKP 384
            ...|...  .:.||:::.:||.|::..:.|:||:|::|:||.:||::|:..||||.|...|.|:|
  Rat   322 SMSPQQE--QAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQP 384

  Fly   385 RI-RHTEARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPR 448
            .. :.||.||....:.:....|..|:...::..:..|:||..::|.|:..|.::|:|.||||.|.
  Rat   385 WFPQLTETRAIMLSRSLAFAYGLVCLGMAYVSSHLGSVLQAALSIFGMVGGPLLGLFCLGMFFPC 449

  Fly   449 CNAKTAVTSIIVSVVAMVWI------------IANGQMNFKSGLIKYEVLPNSLDQCEARGLYMI 501
            .|...|:..::..:....||            .|:..:|..|..     ||::|
  Rat   450 ANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAAASPPLNGSSSF-----LPSNL----------- 498

  Fly   502 AEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDE 566
             .....|...|.|:..|:|..           ..|.:|:.||....|..|....:.:|.:.....
  Rat   499 -TVATVTTLMPSTLSKPTGLQ-----------QFYSLSYLWYSAHNSTTVIAVGLIVSLLTGGMR 551

  Fly   567 NEKQNPKLYSPFVRKFLS-LPVTDQ 590
            ....||....|.:.|.|: ||::.|
  Rat   552 GRSLNPGTIYPVLPKLLALLPLSCQ 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	174/553 (31%)
Slc5a6	NP_570102.1	SLC5-6-like_sbd	23..548	CDD:382020	175/558 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920