Protein Alignment CG2187 and LOC1277620

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_317094.5
• Gene: LOC1277620 / 1277620
• VectorBaseID: AGAMI1_007213
• Length: 684
• Species: Anopheles gambiae
• Alignment Length: 629
• Identity: 209/629 - (33%)
• Similarity: 361/629 - (57%)
• Gaps: 42/629 - (6%)

  Fly     2 STTTTTTTTMA-SAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSK-NTTEEYLRGGK 64
            ||.|.|.:.:| |.:|:.::.|.|...||.:|.::|..|..|||||||.||.| |..:|||.|||
Mosquito    86 STVTATESILATSTMSTITEALLFSWFDYTIFALLLLLSTFIGVYFGFLSKIKQNNKKEYLLGGK 150

  Fly    65 KMQTLPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNC 129
            .|...|::.||:||.:|||.::.:|:|.|::|..|...::....|..::..|.:||||:..|::.
Mosquito   151 TMNKFPVSASLIASHVSGITMLGVPSEMYSHGTQYWMFIIPAFTVALLMKTIYLPVFYDLQVTSA 215

  Fly   130 YEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLG 194
            :.|||:||:|..|...:..:.....:.:|:.:::|:|||:||||:|:|:|..::..||||||.:|
Mosquito   216 FTYLELRFDKFVRSAASLVYALQCIIYIPIVIYVPALAFSQVTGVNLHVITPIICVICIFYTTVG 280

  Fly   195 GIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFNFDFGLDPR--IRMTFWG 257
            |::||||||.:|..:|:.:.:||.|||....||...|.|.|..|.|..| |.:||.  :|.:||.
Mosquito   281 GLRAVVWTDTLQFVLMIGACIAVIVLGISSVGGFMEVWEAADRGKRLIF-FNMDPNPFVRTSFWT 344

  Fly   258 ATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCD 322
            ...|...:|..::.:||.||||.:::|....||.|||:...|.:.:...:...|::::|:|..||
Mosquito   345 VCFGLTTLWVSNLAVNQGCVQRFLAVPDLRVAKNSLIIFTAGLIFVKSCSCFIGLLIYAKYESCD 409

  Fly   323 PMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIR 387
            |.....::|.|:::|:::.|:...:.|:||:|:|.:||||||::|:.||:|||.:|.|:|..|:.
Mosquito   410 PYSTHKITKIDQILPYYIMDVGSKIPGLPGLFVSGIFSAALSTMSSVLNTLAGTIYEDFIHHRMP 474

  Fly   388 H-TEARANWAMKLIVVVMGGYCILG-GFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCN 450
            : :|.:|:..||::|||: |:.:|| .|:.:....::...::.:|:.:|.::|:|..||...|.|
Mosquito   475 NASEKKASNIMKMLVVVL-GFLVLGLVFVAERMGQVMHIAISSSGVTSGTMLGMFTAGMISRRMN 538

  Fly   451 AKTAVTSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTM 515
            .|..:::.:||:|....|:...|:|.|.     .:||...|.|:|..:..:...::.|  .|.|:
Mosquito   539 TKGIISAAVVSMVLTGTIMTGAQLNPKP-----PMLPLRTDGCDAGVIANVTSILSST--VPETV 596

  Fly   516 KPPSGAPVTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPFVR 580
            :            .|....::.:||..|.:||....|:.|..:|.:  ....:..:.:|.:||.|
Mosquito   597 E------------GDTIPLIFKLSFMHYSLLGLITFFVVAFVVSEL--TGGGDISDERLLAPFRR 647

  Fly   581 ------KFLSLPVTDQDLEEVPLRGSKVAATPDLRIEPTEKEKQ 618
                  |.::|...:...||:.:      |..:|: :|::.||:
Mosquito   648 SPEKLEKEMTLLKHNIKYEEIDM------ALKELQ-KPSDMEKK 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	187/538 (35%)
LOC1277620	XP_317094.5	None