Protein Alignment CG2187 and LOC1277592

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_317064.5
• Gene: LOC1277592 / 1277592
• VectorBaseID: AGAMI1_010084
• Length: 597
• Species: Anopheles gambiae
• Alignment Length: 625
• Identity: 229/625 - (36%)
• Similarity: 364/625 - (58%)
• Gaps: 47/625 - (7%)

  Fly     6 TTTTTMASAVSS-ASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSK-NTTEEYLRGGKKMQT 68
            |.::||..|..: ..|.|.|...||.:|..|||.||.||||:|||:|.| |.|.|||.|.|:|:.
Mosquito     4 TVSSTMEEATEAPLEQRLLFSPIDYVIFCSMLGMSALIGVYYGFFAKQKQNNTAEYLLGSKQMKV 68

  Fly    69 LPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYL 133
            .|:|:||.|:.:|.|.::.:|||.|.||..|....::.|:|...::|:.:|||:|....:||.|:
Mosquito    69 FPVAMSLTATHISAITMLGVPAEMYKYGIQYWACSISGLIVTIFMVYVFLPVFHELQTVSCYSYI 133

  Fly   134 EMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKA 198
            |.||:||||.|.:..|:....|..||.::.|::||:||||:|:|:|..::..||||||..|||:|
Mosquito   134 EQRFDKRTRTLASGLFMFYCLLNTPVIIYAPAIAFSQVTGINVHIITPIICCICIFYTTFGGIRA 198

  Fly   199 VVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGR---FNFDFGLDPRIRMTFWGATM 260
            |:|||.:|...||.::..|..|||::.||:..|...|..|||   ||.|  .||.:|.:||..::
Mosquito   199 VIWTDTLQFGAMLCALFVVMTLGTLQLGGVVNVFRLAEAGGRLIWFNMD--PDPYLRTSFWLVSV 261

  Fly   261 GGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCDPML 325
            |...||..:||:...|:||.:::|..|.|||::.:.|:|.:::..|:..:|:::|.:|:.|||:.
Mosquito   262 GLTSMWISNIGVTPECIQRFLTIPDMSSAKKAVWIFGVGHILVKLFSVYNGLLIFGKYHDCDPIH 326

  Fly   326 AGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIRHTE 390
            .|.|.|.|::..::|.|:..|:.|:||:|:..:|||||||:|.::|:|:|.::.|:|:||....:
Mosquito   327 EGTVQKYDQIFAYYVLDVARHIPGLPGLFVVGIFSAALSSMSTSMNTLSGTLFEDFIRPRFALKD 391

  Fly   391 ARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAV 455
            ..|:..:|::|:.:|..|:|..|:|:...||....::::|:.:|.::|:|.||||.|..|.|.|.
Mosquito   392 KTASTVVKVMVMTIGVICLLLVFVVEQLGSIFSLAISVSGVTSGTMLGIFFLGMFSPHINGKGAF 456

  Fly   456 TSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSG 520
            ...|||::::..|....|:....|.:|||.||...|.|              :||. ||
Mosquito   457 WGAIVSLISLSVIAVGAQLEILGGHLKYESLPFRYDGC--------------SDFN-VT------ 500

  Fly   521 APVTTAFHSD---RDFS----LYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPF 578
            ...|:.|:.|   .|.|    ::.|.|.:|.:||:.:|.:..|.:||. ...:.|:....|.:|:
Mosquito   501 GTETSTFYRDAAGHDNSEVPWVFRIGFMYYSLLGTIIVIVVGIVVSYA-TGGQKERVPLNLLTPW 564

  Fly   579 VRKFLSLPVTDQDLEEVPLRGS-KVAATPDLRIEPTEKEK 617
            ||...      :.|:..|.:|. |:..:    .|.||.||
Mosquito   565 VRPLY------RSLDYTPEKGEYKLTRS----CEMTEIEK 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	207/544 (38%)
LOC1277592	XP_317064.5	None