Protein Alignment CG2187 and LOC1273345

DIOPT Version :10

• Sequence 1: NP_651890.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_312311.5
• Gene: LOC1273345 / 1273345
• VectorBaseID: AGAMI1_015159
• Length: 607
• Species: Anopheles gambiae
• Alignment Length: 616
• Identity: 304/616 - (49%)
• Similarity: 403/616 - (65%)
• Gaps: 28/616 - (4%)

  Fly    11 MASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKN-TTEEYLRGGKKMQTLPIAIS 74
            |..::::..|. :|.:.||.||.||||.|..||||||||.|.|| ||||||.||:||:|.|||||
Mosquito     1 MVKSITANPQG-QFSVEDYAVFTIMLGISTAIGVYFGFFQKKKNQTTEEYLLGGRKMKTFPIAIS 64

  Fly    75 LVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFNK 139
            |:||||||::|||:|||.|:||..|..:...|:::..|:.||.|||||.|:::|||:|||.||:.
Mosquito    65 LIASQLSGVSIMSVPAEMYSYGAQYWIIAPTMILITMIINYIFVPVFYNNHITNCYQYLEDRFSP 129

  Fly   140 RTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDV 204
            ..::.|||.:|.|.:|:||:::|||:|||:||:|:||||||.:|..:||||||||||||||||||
Mosquito   130 AVKKFVTFTYVLNIYLILPIFIFIPALAFSQVSGINIHLINGIVCGVCIFYTMLGGIKAVVWTDV 194

  Fly   205 VQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFN-FDFGLDPRIRMTFWGATMGGIFMWTG 268
            |||.||.:|...|.|:|..:.||:..|:|||:.|.|.. ||..||...|.|||.|::|.:|:|||
Mosquito   195 VQGLIMFVSCFLVVVIGVAKIGGLSEVLERAAAGNRLEIFDMTLDATTRQTFWTASVGNLFLWTG 259

  Fly   269 HIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCDPMLAGLVSKPD 333
            ::||:|||||||||:||.|||:.:|.:...||::|...|..:||::||:|:.|||:..|||.|.|
Mosquito   260 YLGLSQSCVQRIVSVPSMSHARAALWIFCAGFIVIMTLNCFTGIVIFAKYFDCDPIKVGLVQKAD 324

  Fly   334 KMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKP--RIRHTEARANWA 396
            |::||||||::|:|.|||||||||||||.||::||.||||||::|.|||:|  ..:||:|.||..
Mosquito   325 KLLPFFVQDVVGNLKGMPGVFISCVFSAGLSTMSANLNSLAGLIYEDYIRPFKLFKHTDASANTT 389

  Fly   397 MKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIVS 461
            ||::::|.|.|||..|.:|:.|..|||.||||..:..|||:|:|.|||..|..|...|:.....|
Mosquito   390 MKVLILVSGVYCIAMGLIVEQFGHILQMVVTIASVTQGAVMGIFCLGMLWPWANKHGALWGSASS 454

  Fly   462 VVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSGAPVTTA 526
            |:.|.||||..|:...:..|.|...|.|:|.|     |.....:...|| |....||..|
Mosquito   455 VIVMSWIIAGAQIAISNKEISYPPKPTSVDGC-----YEYGYNVTSNDF-PTLEAPPDEA----- 508

  Fly   527 FHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPFVRKFLSLPVTDQD 591
                 :||:|:|||.||..:|:.:|||..||:||.....:.....|||.||.|...|...|...|
Mosquito   509 -----EFSIYNISFVWYSTVGTFMVFLVGIPVSYFTGSQDLRNFRPKLISPLVHWLLPEEVLQND 568

  Fly   592 LEEVPLRGSKVAATPDLRIEPTEKEKQTVTE 622
            .       |..|....|..||.::...|..|
Mosquito   569 F-------SLKAENEKLNPEPIKEWTFTAHE 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_651890.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	284/537 (53%)
LOC1273345	XP_312311.5	SLC5sbd_NIS-SMVT	17..538	CDD:271383	284/536 (53%)