Protein Alignment CG2187 and SLC5A10

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 678
• Identity: 136/678 - (20%)
• Similarity: 257/678 - (37%)
• Gaps: 180/678 - (26%)

  Fly    16 SSASQDL-----RFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISL 75
            ::::.||     :..:.|..|..:....:..:|:: .....|:||...|...|:.|...||..||
Human     3 ANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIW-SSCRASRNTVNGYFLAGRDMTWWPIGASL 66

  Fly    76 VASQ--------------LSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNV 126
            .||.              ..|:|:..       :.:|..:|:||       |.::.||::..:.:
Human    67 FASSEGSGLFIGLAGSGAAGGLAVAG-------FEWNATYVLLA-------LAWVFVPIYISSEI 117

  Fly   127 SNCYEYLEMRF-NKRTRQ-LVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIF 189
            ....||::.|: .:|.|. |.....:.:.|..:.:.::..:|......|.|.:|..::...|...
Human   118 VTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITAL 182

  Fly   190 YTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERA------------------- 235
            ||:.||:.||::||.:|..||::..|.:.:....:.|| :..:|.|
Human   183 YTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGG-YGQLEAAYAQAIPSRTIANTTCHLPR 246

  Fly   236 SDGGRFNFDFGLDPRIRMTFW-GATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSG-- 297
            :|.    .....||......| |.|.|...|.|.:...:|..|||.:|....:|||...|::.
Human   247 TDA----MHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYL 307

  Fly   298 ----LGFLIISFFNTISGIIMFARYYGC---DPMLAGLVSKPDKM-------------------- 335
                :|.:|      :.|:|..|.:.|.   :......||:.|.:
Human   308 KMLPMGLII------MPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSN 366

  Fly   336 --MPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDY---IKPRIRHTE----- 390
              .|..|.::|.  .|:.|:.|:.:.:|.:|||::..||.:.:...|.   ::||....|
Human   367 IAYPKLVMELMP--IGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVG 429

  Fly   391 ------------ARANWAMK------------------LIVVVMGGYCILGGFMVQNFNS--ILQ 423
                        :|.::.:.                  |::|.:.|..:....::|:.||  :..
Human   430 RTGIPSTPPAPQSRLSFLLPETPPLERYLLGLVVMDLWLVIVALIGVSVAWIPVLQDSNSGQLFI 494

  Fly   424 TVVTITGINTGAVVGVFLLGMFVPRCNAKTA----VTSIIVSVVAMVWIIAN-----GQMNFKS- 478
            .:.::|......|..||:||:|..|.|.:.|    :..::|....:|....|     |:.:.:.
Human   495 YMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPA 559

  Fly   479 --GLIKYEVLPNSLDQCEARGLYMIAEAI-----------NKTDFT---PVTMKPPSGAPVTTAF 527
              |.|.|  |..::......|..::|.::           |.|.:|   .|.:...:|...|...
Human   560 VLGSIHY--LHFAVALFALSGAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQK 622

  Fly   528 HSDRDFSLYDISFYWYKVLG-SALVFLC 554
            |:           :|.:|.| :|::.:|
Human   623 HA-----------FWARVCGFNAILLMC 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	134/662 (20%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:320982	134/664 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146411
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740