Protein Alignment CG2187 and slc5a10

DIOPT Version :9

• Sequence 1: NP_001189331.1
• Gene: CG2187 / 43743
• FlyBaseID: FBgn0017448
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_017211446.2
• Gene: slc5a10 / 100007379
• ZFINID: ZDB-GENE-110922-5
• Length: 637
• Species: Danio rerio
• Alignment Length: 670
• Identity: 153/670 - (22%)
• Similarity: 265/670 - (39%)
• Gaps: 170/670 - (25%)

  Fly     8 TTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSK---SKNTTEEYLRGGKKMQTL 69
            :||...|:|.:     |.::|    :|::||...:.|..|.:|.   |:||...|...|:.|...
Zfish     5 STTKFFALSQS-----FSVSD----IIVIGAYFLLNVAVGIWSSCRVSRNTLSGYFLAGRDMAWW 60

  Fly    70 PIAISLVASQ--------------LSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPV 120
            ||..||.||.              ..|||:..       :.:|..:.:||       |.::.|||
Zfish    61 PIGASLFASSEGSGLFIGLAGTGAAGGIAVAG-------FEWNATYALLA-------LAWVFVPV 111

  Fly   121 FYENNVSNCYEYLEMRF-NKRTRQLVTFFFVTNSFLMLPVYMFIPS-----LAFAQV-TGMNIHL 178
            :..:.:....|||..|| .:|.|     .:::...|:|.|:..|.:     ..|.|| .|.|::|
Zfish   112 YVSSGIVTMPEYLGRRFGGERIR-----MYLSALSLLLSVFTKISTDLYSGALFVQVCLGWNLYL 171

  Fly   179 INVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTV------------ 231
            ..|::..:...||:.||:.||::||.:|..||::..|.:.:....:.||...:
Zfish   172 STVLMLVVTALYTIAGGLAAVIYTDTLQTFIMIIGAVILTITAFNKIGGYSNLESVYLQAVPSKI 236

  Fly   232 -------MERASDGGRFNFDFGLDPRIRMTFW-GATMGGIFMWTGHIGLNQSCVQRIVSLPSYSH 288
                   :.|......|.     ||......| |.|:|...:.|.:...:|..|||.:|..|.||
Zfish   237 IPNTTCHLPRHDAMHLFR-----DPVHGDLPWPGMTLGLTIIATWYWCTDQVIVQRSLSAKSLSH 296

  Fly   289 AKKSLIVSGLGFLIISFFNTISGIIMFARY---YGC-DP-----MLAGLVSKPDKMMPFFVQDIM 344
            ||.:.|.:....|:...|..:.|:|..|.|   ..| ||     :....|...:...|..|.::|
Zfish   297 AKGASIFASYLKLLPMMFIILPGMISRALYPDTVACVDPEECVKVCGAEVGCSNIAFPKLVIELM 361

  Fly   345 GHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFD-YIKPRIRHTEARANWAMKLIVVVMGGYC 408
            .  :|:.|:.|:.:.:|.:|||::..||.:.:...| :.|.|...:|.......:::.|::....
Zfish   362 P--SGLRGLMIAVMMAALMSSLTSIFNSSSTLFTMDIWKKYRRGASEKELLLVGRIVTVILVVIS 424

  Fly   409 ILGGFMVQNFNS-----ILQTVVT-----ITGINTGAV-------VGVF---LLGMFV------- 446
            ::...::|:.||     .:|:|.:     :|.|...||       .|.|   ::|:.|
Zfish   425 VVWIPILQSANSGQLYVYIQSVTSYLAPPVTAIFVMAVFWKRTNEAGAFWGLMVGLVVGLTRMVL 489

  Fly   447 ------PRCNA-------------------KTAVTSIIVSVVAMV-------------WIIANGQ 473
                  |||..                   ..|:|:|:|:|::::             |...:..
Zfish   490 EFAFPPPRCGVFDPAPSVLRSMHYLHFAIILCALTAIVVAVISLLTPPPTEEQTRNLTWWTLHNS 554

  Fly   474 MNFKSGLIKYEVLPNSLDQCEA--RGLYMIAEAINKTDF-TPVTMKPPSGAPVTTAFHSDRDFSL 535
            ...:..|.|...|....|.||:  ||     :.:....| :|...:..||.| ....||..:
Zfish   555 TEREIPLQKVSTLSRRTDGCESVRRG-----KCVRTAGFCSPRPGRFASGTP-PPIIHSTTE--- 610

  Fly   536 YDISFYWYK-VLGSALVFLC 554
               ..:|.: ...:|::.:|
Zfish   611 ---DPFWSRFCCVNAIILMC 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	148/651 (23%)
slc5a10	XP_017211446.2	SLC5sbd_SGLT5	17..637	CDD:212058	148/653 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580029
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740