Protein Alignment salt and Slc5a4b

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_075708.2
• Gene: Slc5a4b / 64454
• MGIID: 1890478
• Length: 660
• Species: Mus musculus
• Alignment Length: 523
• Identity: 120/523 - (22%)
• Similarity: 216/523 - (41%)
• Gaps: 89/523 - (17%)

  Fly     8 LASTVATATTATLEDLHFSLTDYIVFSLMLSASAGIGV---YF------GFFSKAKN---TTEEY 60
            :|||::.:.|...|:..       |..:.:..:|.|.|   ||      |.:|..::   |...:
Mouse     1 MASTLSPSITPQTEEPP-------VVPVRIQNAADISVIVIYFIVVLAVGLWSMVRSNRGTVGGF 58

  Fly    61 LQGGKRMPTLPVAISLVSSQLSGVAMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDN 125
            ...|..|...|:..||.:|.:.....:.:.....:.|..:..|.|..:|.|.||.::.:|::...
Mouse    59 FLAGHDMAWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVEWNALLMVLVLGWVFLPIYIKA 123

  Fly   126 NVSNCYEYLELRFSKRTRQLVTITFILNQFLMLPV----YMFVPSLAFSQVTGYNIHLINTVVSS 186
            .|....|||..||..:..|:  ...:|:.|:|:.:    .:|..::......|.|::|...::.:
Mouse   124 GVLTMPEYLRKRFGGKRLQI--YLSVLSLFIMVALQTSSIIFSGAIFIQLALGLNLYLAVFILLA 186

  Fly   187 ICVFYTMLGGIKAVVWTDVVQGSVMLISVVLVAILGTSNTGG-------ITNVLENAAEGGRFDF 244
            |..|||:.||:.:|::||.||..:||:..:::.....:..||       ..|.:.:..||.....
Mouse   187 ITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAIPSVVEGDNLTI 251

  Fly   245 ----------SFGI--DPRLRLTFISGMASGLLMWTGKL-GL----------DQSCVQRIVSLPS 286
                      ||.:  ||          .:|.:.|.|.: |:          ||..|||.:...:
Mouse   252 SPKCYTPQPDSFHVFRDP----------VTGDIPWPGLIFGMTILAIWYWCADQVIVQRCLCGKN 306

  Fly   287 YGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDK-----------LMPFF 340
            ..|.|...::.|...||.|......|:|....|  .|.:...:.|:.:|           ..|..
Mouse   307 MSHVKAACILCGYLKLLPMFLMVMPGMISRILY--TDKVACVVPSECEKQCGTAVGCTNYAYPTL 369

  Fly   341 IQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFD-YIKPRINHSEAKANATMKLVIVV 404
            :.::|..  |:.|:.:|.:.::.:|||::..||.:.:...| |.|.|...||.:.....::..:|
Mouse   370 VLELMPD--GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKIRKKASERELMIAGRIFGMV 432

  Fly   405 MGAYCIVGGFIVQ-----NFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCL 464
            :.|..|:...:||     .....|.::.:..|..:||   ||.|.:|..|.|.:.|..|:....:
Mouse   433 LIAVSILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGA---VFMLAIFFKRVNEQGAFWGLMVGLV 494

  Fly   465 VML 467
            |.|
Mouse   495 VGL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	115/503 (23%)
Slc5a4b	NP_075708.2	SLC5-6-like_sbd	27..660	CDD:444915	114/490 (23%)