Protein Alignment salt and slc5a11

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001007301.1
• Gene: slc5a11 / 492334
• ZFINID: ZDB-GENE-041114-9
• Length: 668
• Species: Danio rerio
• Alignment Length: 692
• Identity: 153/692 - (22%)
• Similarity: 273/692 - (39%)
• Gaps: 164/692 - (23%)

  Fly     1 MASSVSNLASTVATATTATLEDLHFSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGK 65
            ||::.:..||...| :..|.:....:.||.:|..:.......:|:: ..:...::|.:.|...||
Zfish     1 MAATEAPDASPTPT-SDGTAQQTTLATTDIVVLVIYFLLVLAVGLW-SMWKTKRSTVDGYFLAGK 63

  Fly    66 RMPTLPVAISLVSSQLSGVAMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNC 130
            .|...||..||.:|.:.....:.:.....:.|...:...|..:|.|.|:.::.:|::..:.|:..
Zfish    64 NMTWWPVGASLFASNVGSGHFIGLAGSGAAAGIGAVAYEWNGMLMVLVMGWLFLPIYIASRVTTM 128

  Fly   131 YEYLELRF-SKRTRQLVTITFI-LNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTM 193
            .|||:.|| .||.:..:.:.:: :..|..:.|.|:..::...|...:||:|...::..|...||:
Zfish   129 PEYLKKRFGGKRIQLFLCVLYLFIYIFTKISVDMYAGAVFIQQALQWNIYLAVVLLLGITALYTI 193

  Fly   194 LGGIKAVVWTDVVQGSVMLISVVLVAILGTSNTGGITNVLE------------NAAEGGRFDFSF 246
            .||:.||::||.||..:|:|..:::.....:..||...||:            |...|...|.:|
Zfish   194 AGGLAAVIYTDAVQTIIMVIGALILMGFSFAEVGGFEAVLDKYPQAIPSIRVPNTTCGIPRDDAF 258

  Fly   247 GIDPRLRLTFISGMASGLLMWTGK-LGL----------DQSCVQRIVSLPSYGHAKRCLLMAGVG 300
            .|       |...:.|. |.|.|. ||:          ||..|||.::..:..|||...|:|  .
Zfish   259 HI-------FRHPVTSD-LPWPGVILGMSIPSMWYWCSDQVIVQRSLAAKNILHAKGGSLLA--A 313

  Fly   301 FLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSK---PDKL---MPFFIQDIMGHMM---------- 349
            ::.::.|  |..:|            .|::|:   ||::   .|...:::.|:.:
Zfish   314 YIKVLPF--FMMVI------------PGMISRILYPDEVGCGDPEVCKEVCGNSVGCSDIAYAKL 364

  Fly   350 -------GMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINHSEAK-----ANATMKLVI 402
                   |:.|:.::.:.:|.:|||::..||.:.:...|..: .|.|:.::     ......||:
Zfish   365 VMELLPAGLRGLMMAVMLAALMSSLTSIFNSSSTIFTMDLWR-NIRHTASEWELMIVGRVFVLVL 428

  Fly   403 VVMGAYCI------VGG--FI-VQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVA--- 455
            ||:....|      .||  || :|:.:..:|...|:          :|..|.|..|.|.|.|
Zfish   429 VVVSVLWIPLVQASQGGQLFIYIQSISMYLQPPITV----------IFVAGCFWKRTNEKGAFWG 483

  Fly   456 -VSGIAFSCLVMLWIIING-----QMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNV 514
             :.|:|..|..|:...|..     :.:.:..:|||         .....|.:||..:....|..|
Zfish   484 LMVGMAVGCTRMILDFIYPTPQCYESDTRPDIIKY---------VHFLYFSIILTILTLVVVVCV 539

  Fly   515 G-TTAIPSLEAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPK 578
            . .|..|..|....||                 ||....|:              ::.||..:.:
Zfish   540 SLATEKPKPEQISRLT-----------------WYTRFDAV--------------IESEEVVSSE 573

  Fly   579 LYSPFVRSMLNKPSPVLELEELPLKTPLSEEQIKEKENGSAT 620
            ||:      ::....|.|.|.||         .||..:||.:
Zfish   574 LYT------IDNDIKVRENEALP---------AKEDSSGSVS 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	134/609 (22%)
slc5a11	NP_001007301.1	SLC5sbd_SGLT6	28..668	CDD:271381	146/664 (22%)