DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment salt and CG2187

DIOPT Version :9

Sequence 1:	NP_651889.3	Gene:	salt / 43742	FlyBaseID:	FBgn0039872	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001189331.1	Gene:	CG2187 / 43743	FlyBaseID:	FBgn0017448	Length:	623	Species:	Drosophila melanogaster

Alignment Length:	625	Identity:	422/625 - (67%)
Similarity:	512/625 - (81%)	Gaps:	10/625 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSVSNLASTVATATTATLEDLHFSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRM 67
            |:.:...:|:|:|.::..:||.|.||||.||.:||.||||||||||||||:||||||||:|||:|
  Fly     2 STTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKM 66

  Fly    68 PTLPVAISLVSSQLSGVAMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYE 132
            .|||:|||||:|||||:|:||:|||:|::|||.||||.||::.:|:||||||||||:||||||||
  Fly    67 QTLPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYE 131

  Fly   133 YLELRFSKRTRQLVTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGI 197
            |||:||:||||||||..|:.|.|||||||||:|||||:||||.||||||.:|||||:||||||||
  Fly   132 YLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGI 196

  Fly   198 KAVVWTDVVQGSVMLISVVLVAILGTSNTGGITNVLENAAEGGRFDFSFGIDPRLRLTFISGMAS 262
            |||||||||||::||:|||.|.:|||..:||:..|:|.|::||||:|.||:|||:|:||......
  Fly   197 KAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFNFDFGLDPRIRMTFWGATMG 261

  Fly   263 GLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQA 327
            |:.||||.:||:|||||||||||||.|||:.|:::|:|||:|..|...:||||||.||||||:.|
  Fly   262 GIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCDPMLA 326

  Fly   328 GLVSKPDKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINHSEA 392
            ||||||||:||||:||||||:.|||||||||||||:||||||:|||.|||||||||||||.|:||
  Fly   327 GLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIRHTEA 391

  Fly   393 KANATMKLVIVVMGAYCIVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVS 457
            :||..|||::||||.|||:|||:|||||||:||:.||||||.|||||||.|||||||||||.||:
  Fly   392 RANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVT 456

  Fly   458 GIAFSCLVMLWIIINGQMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIPSL 522
            .|..|.:.|:|||.|||||||:|||||:.|||.||||||:|..:|..||...:.|.|  |..|..
  Fly   457 SIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPV--TMKPPS 519

  Fly   523 EAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYSPFVRSM 587
            .||  :||||.|:||||:||.|||||||||:.|||..|||:||:|..|:.|||||||||||||..
  Fly   520 GAP--VTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPFVRKF 582

  Fly   588 LNKPSPVLELEELPLK------TPLSEEQIKEKENGSATE 621
            |:.|....:|||:||:      ||....:..|||..:.||
  Fly   583 LSLPVTDQDLEEVPLRGSKVAATPDLRIEPTEKEKQTVTE 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	384/537 (72%)
CG2187	NP_001189331.1	SLC5sbd_NIS-SMVT	27..561	CDD:271383	384/537 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468689
Domainoid	1	1.000	45	1.000	Domainoid score	I12178
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	1	1.000	-	-		H64794
Inparanoid	1	1.050	579	1.000	Inparanoid score	I2526
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	11	10.900