Protein Alignment salt and slc5a8

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001351880.1
• Gene: slc5a8 / 394505
• XenbaseID: XB-GENE-479634
• Length: 620
• Species: Xenopus tropicalis
• Alignment Length: 632
• Identity: 200/632 - (31%)
• Similarity: 315/632 - (49%)
• Gaps: 63/632 - (9%)

  Fly    25 FSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSV 89
            |::.||:||:|||..||.||:|:.|....:.|::::|.||:.|..:|||:||.:|.:|.|.::..
 Frog    10 FTVWDYVVFALMLLISAVIGIYYAFAGGGQKTSKDFLMGGRSMTAVPVALSLTASFMSAVTVLGT 74

  Fly    90 PAETYSFGFNMIFVVWAMVLSVPVLI--YIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFIL 152
            |||.|.||  .:|.::|...::.|:|  .:.:||||...:::.||||||||:|..|.|.||.||:
 Frog    75 PAEVYRFG--SMFSIFAFTYAIVVVISSEVFLPVFYRLGITSTYEYLELRFNKFVRLLGTILFII 137

  Fly   153 NQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVL 217
            ...|...:.::.|:||.:||||:::.........:|.||..:||:||||||||.|..:|:.....
 Frog   138 QTVLYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTMGGLKAVVWTDVFQVGIMVAGFSS 202

  Fly   218 VAILGTSNTGGITNVLENAAEGGRFDF-SFGIDPRLRLTFISGMASGLLMWTGKLGLDQSCVQRI 281
            |.|......|||..:|.::..|.|.:| .|..:|..|.:|.:.:..|...|||..|::||.|||.
 Frog   203 VIIRAVVVQGGIGPILNDSYYGDRLNFWDFTPNPLQRHSFWTIVVGGTFTWTGIYGVNQSQVQRY 267

  Fly   282 VSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQDIMG 346
            ::..:...||..|.:..:|...|::....:|:.|::.|..|||..|..||.||:|||:...||:.
 Frog   268 IACKTRFQAKLSLYINLLGLWAILACAVLSGLAMYSIYKDCDPWTAQFVSAPDQLMPYLSLDILR 332

  Fly   347 HMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINH-SEAKANATMKLVIVVMGAYCI 410
            ...|:||:|:||.:|.:||::|:|:|:.|.|...|.|||.... ||.|.:...|...::.||.||
 Frog   333 DYPGLPGLFVSCAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSETKMSWISKGTSLIYGAICI 397

  Fly   411 VGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQM 475
            ....:......::|...:|.|:..|.::|:|.||:..|..|:..||.|:.....:.||:.|..|:
 Frog   398 AMAGLASLMGGLLQAALSIFGMVGGPLLGLFALGIIFPFVNSLGAVIGLLSGFAISLWVGIGSQI 462

  Fly   476 ---NFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELTTAFDSNRD 537
               ...:.|    |.|..|:.|....||    :.....|..:.||.||.:.:..||..::
 Frog   463 YPPTASSSL----PKPLSLEGCNFTSFE----SNWTTTVMPMMTTLIPEVSSRPELADSW----- 514

  Fly   538 FSIYDTSFYWYKVLGALLVFAWAI----------------------PMSYVWPL----------D 570
               |..|:.::..||.::.....:                      ..||:..|          :
 Frog   515 ---YSLSYLYFSTLGTIVAVVVGVIASLLSGGLKQNVNRDFLLTSQDFSYLNVLFSNCKKKGQEE 576

  Fly   571 KEEKQNPKLYSPFVRSMLNKPSPVLELEELPLKTPLSEEQIKEKENG 617
            |.|..|.|:.|..........:|.....|      :|..:.|||.||
 Frog   577 KVEVLNWKMRSTDTDMDQGTDNPAFNHME------MSSTEKKEKMNG 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	184/566 (33%)
slc5a8	NP_001351880.1	SLC5sbd_SMCT1	7..547	CDD:271402	184/554 (33%)