Protein Alignment salt and Slc5a12

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001102058.1
• Gene: Slc5a12 / 362188
• RGDID: 1311652
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 562
• Identity: 191/562 - (33%)
• Similarity: 300/562 - (53%)
• Gaps: 30/562 - (5%)

  Fly    25 FSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSV 89
            |...||:||:.:...|:||||:|....:.|.|:.|:|.||::|...|||:||.:|.:|.|.::..
  Rat     6 FEAWDYVVFAALFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFAPVALSLTASFMSAVTVLGT 70

  Fly    90 PAETYSFGFN-MIFVV-WAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFIL 152
            |||.|.||.: :||:: :|.|:.....:::  ||||.:.:::.||||:|||:|..|...||.:||
  Rat    71 PAEVYRFGASFLIFLISYAFVVFFTSELFL--PVFYRSGITSTYEYLQLRFNKPVRYAATIIYIL 133

  Fly   153 NQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVL 217
            ...|...|.::.|:||.:||||:|:.........:|.||..|||:|||||||..|..||::..:.
  Rat   134 QTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLT 198

  Fly   218 VAILGTSNTGGITNVLENAAEGGRFDF-SFGIDPRLRLTFISGMASGLLMWTGKLGLDQSCVQRI 281
            |.|.|:::.||..||||.|..|.|.|. .|.:||..|.||.:....|...|.|..|::||.:||.
  Rat   199 VLIQGSNHVGGFDNVLEQARNGSRLDIVDFDVDPLRRHTFWTIAVGGTFTWLGIYGVNQSTIQRC 263

  Fly   282 VSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQDIMG 346
            :|..:..|||..|....:|..:|:....|.|:||:|||..|||..:|.:..||:|||:|:.:|..
  Rat   264 ISCKTEKHAKLALYFNLLGLWIIVVCAVFCGLIMYAYYKDCDPWTSGAILAPDQLMPYFVMEIFA 328

  Fly   347 HMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINH-SEAKANATMKLVIVVMGAYCI 410
            .|.|:||:|::|.||.:||:::||:|:.|.|.:.|::|....| |:..:....|.:.::.|..|.
  Rat   329 TMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDTLSTWISKGLCLLFGIICT 393

  Fly   411 VGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQM 475
            ....:.....|::|...:|.|:..|.::|:|.||:..|..|.|.|:.|:.....:..|:.| |..
  Rat   394 SMAVLASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTGITLSFWVGI-GAF 457

  Fly   476 NFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELTTAFDSNRDFSI 540
            .:.|...|..|||...:.|..:               |..||....|.:...|...:
  Rat   458 VYPAPDSKTLPLPLSTEFCVQQ---------------NKTTTEAYQLSSRPVLADTW-------- 499

  Fly   541 YDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYSP 582
            |..|:.::..:|.|...|..|.:|::....:.:..:|.|..|
  Rat   500 YSLSYLYFSAVGCLGCIAAGIIISFLTGRQRGKDVDPLLIRP 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	187/541 (35%)
Slc5a12	NP_001102058.1	SLC5sbd_SMCT2	3..527	CDD:212089	188/546 (34%)