Protein Alignment salt and Gm5134

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_006513854.1
• Gene: Gm5134 / 333669
• MGIID: 3646667
• Length: 695
• Species: Mus musculus
• Alignment Length: 680
• Identity: 146/680 - (21%)
• Similarity: 249/680 - (36%)
• Gaps: 121/680 - (17%)

  Fly    23 LHFSLTDYIV--FSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVA 85
            || |.||.:|  |.|:|....|:   :...|.::.|.:::...|:.:....:.||:.||.:....
Mouse    21 LH-STTDTLVMTFYLLLVVCVGL---WALLSHSRGTVKDFFLAGQNLAWWLMGISIYSSNIGSGH 81

  Fly    86 MMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITF 150
            .|::.....:.|..:..:.|..:..:.:|.:|.||::....|....|||:.||.....||. .||
Mouse    82 YMALAGIGAASGIAVGALEWNSIFMLFLLGWIFVPIYSKAEVVTLPEYLKKRFGSLRIQLF-FTF 145

  Fly   151 ILNQFLMLPVYMF--------VPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQ 207
            |   ||:  ||:|        ..::....|...:|:.....|.:|...||:.||:..|.:.:.:|
Mouse   146 I---FLI--VYIFSRISMEIGFGAMFLKMVWDTDIYQTMLTVLTIIGMYTITGGLATVAYVESLQ 205

  Fly   208 GSVMLISVVLVAILGTSNTGGITNVLENAAEG-------GRFDFSFGIDPRLRLT------FISG 259
            ..:|::...|:........||...::....|.       |    ::...|...|.      ....
Mouse   206 AGIMILGSALLMGYAFYEVGGYPKLVSKYMEAIPSKTQQG----NWTAQPECYLPRQDAFHIFRS 266

  Fly   260 MASGLLMWTGK-LG----------LDQSCVQRIVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGI 313
            ..||.:.|.|. ||          .||..|||.::..|..|.:...|:.|...||.|......|:
Mouse   267 CVSGDIPWPGLILGATTVSLFYGCADQVSVQRFLAGKSRLHMEGGCLLCGYLKLLPMFLMVMPGM 331

  Fly   314 IMFAYYYGCDPIQAGLV--SKPDKL-----------MPFFIQDIMGHMMGMPGVFISCVFSASLS 365
            |....|    |.|...|  |:..|.           .|..:..:|.|  |:.|..:|.|.::.:|
Mouse   332 ISRILY----PDQVACVVPSECQKFCGRGTGCSALAYPVLVLGVMPH--GLQGFMLSTVCASLMS 390

  Fly   366 SLSASLNSFAGVV---YFDYIKPRINHSEAKANATMKLVIVVMGAYCIVGGFIVQNF-NSII-QT 425
            ||::..||.:.:.   .:.:|:|.....|.....  :..::::.|..||...|::.. |.|: :.
Mouse   391 SLTSIFNSSSALFTLNIYTWIRPTATEKELMIAG--RFFVIILLAVTIVWIPIIEMAPNEILFEY 453

  Fly   426 MWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQMNFKAGLIKYDPLPNG 490
            |..:......::..||.|.:|..|.|.:.|..|:.....:       |.....|... |.|:..|
Mouse   454 MQVLKSCLTPSMTAVFLLAVFCKRVNEQGAFWGLIVGTTI-------GVFRLLAEFF-YGPVTCG 510

  Fly   491 LD-QCEA---------KGFEVILNAIRNKNVTNVGTTAIP---------SLEAPKELTTAFDSNR 536
            .| ||..         .||.:.|..|......::.|..||         ||...::...|.|...
Mouse   511 RDRQCPIFICGLHYLYFGFCLFLVTILIILAISLATEPIPDHHLHGLCWSLRNSQQRRVALDKEM 575

  Fly   537 DFSIYDTSFYWYKVLGALLVFAWAIPMSYVW---------------PLDKEEKQNPKLYSPFVRS 586
            .:..:.:......:.|......|..     |               |.:..||:....:...|.|
Mouse   576 RWKAFPSFTSQPGMFGEAHTCLWKF-----WDLFCGLDSQSKCKTGPENATEKELEDTWKKVVSS 635

  Fly   587 MLNKPSPVLELEELPLKTPLSEEQIKEKEN 616
            ..:....:|.......|:...|:::|:..|
Mouse   636 DRSTAFEILARRMAARKSEEHEDRMKDWSN 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	132/608 (22%)
Gm5134	XP_006513854.1	SLC5-6-like_sbd	26..695	CDD:444915	142/674 (21%)