DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment salt and CG32669

DIOPT Version :9

Sequence 1:	NP_651889.3	Gene:	salt / 43742	FlyBaseID:	FBgn0039872	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_727460.1	Gene:	CG32669 / 326229	FlyBaseID:	FBgn0052669	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	591	Identity:	182/591 - (30%)
Similarity:	295/591 - (49%)	Gaps:	53/591 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSVPAET 93
            ||.:.:::|..|..||:|:.|....::||.|||...:.|...|||.||::|.:|.|.::.|..|.
  Fly     8 DYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVSMEN 72

  Fly    94 YSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFILNQFLML 158
            |.:|...:.:..:.|||.||..|:|:||||....::.||||||||...||...:::|.|...|.:
  Fly    73 YQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQMVLYM 137

  Fly   159 PVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVLVAILGT 223
            .:.::.|:||...|||.:......:|..:|.||..|||:|||:.||:.|..:|..:|..|.|...
  Fly   138 GIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSVIICAW 202

  Fly   224 SNTGGITNVLENAAEGGRFDF-SFGIDPRLRLTFISGMASGLLMWTGKLGLDQSCVQRIVSLPSY 287
            ...|.:..:...|.|.||.:. :|.:||..|.|:.:.:..|...:....|::|:.|||::::.|.
  Fly   203 VKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLMAVKSL 267

  Fly   288 GHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQDIMGHMMGMP 352
            ..|:..|........|:...|||:|:.::.||..|||:..|.|:..|::||.|:.|.||...|:.
  Fly   268 SAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTMGEYTGLA 332

  Fly   353 GVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINHSEAKANAT-------MKLVIVVMGAYCI 410
            |:|:|.:|.||||::|:.::|.|.|...||:||.::.. ||...|       .||:.:..||.||
  Fly   333 GLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCC-AKRTLTDRQTLWYSKLLSLFFGALCI 396

  Fly   411 VGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQM 475
            ...|:..:...::|...:|.||..|.::|:|.|||:|.:.|.|.|:.|:..|.....||   |..
  Fly   397 GMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCFWI---GFG 458

  Fly   476 NFKAGLIKYDPLPNG--LDQCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELTTAFDSNRDF 538
            ..|..|:..|....|  :|:..|:  ::.|                      |.:....:....|
  Fly   459 QPKPPLVSLDMSTAGCPVDRSFAR--DIFL----------------------KTVIAVAEEEHYF 499

  Fly   539 SIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYS--------------PFVRSMLN 589
            .:|..|:.||..||.|:.|.....:|:::.|.|.: .|.::|.              |..:.:..
  Fly   500 YLYRISYMWYAALGFLITFFGGWLLSWLFALLKWD-NNRRIYQDADCTLIKHDLFVPPIAKRLQR 563

  Fly   590 KPSPVL 595
            :..|:|
  Fly   564 RQMPLL 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	175/546 (32%)
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	175/546 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448244
Domainoid	1	1.000	97	1.000	Domainoid score	I370
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900