Protein Alignment salt and Slc5a1

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_037165.1
• Gene: Slc5a1 / 25552
• RGDID: 3713
• Length: 665
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 122/509 - (23%)
• Similarity: 208/509 - (40%)
• Gaps: 65/509 - (12%)

  Fly     6 SNLASTVATATTATLEDLH--FSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMP 68
            |:..|...|||.|.::...  .:..|..|..:.......:|:: ..||..:.|...:...|:.|.
  Rat     3 SSTLSPAVTATDAPIQSYERIRNAADISVIVIYFVVVMAVGLW-AMFSTNRGTVGGFFLAGRSMV 66

  Fly    69 TLPVAISLVSSQLSGVAMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEY 133
            ..|:..||.:|.:.....:.:.....:.|..|....|..::.|.||.::.||::....|....||
  Rat    67 WWPIGASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVLGWLFVPIYIKAGVVTMPEY 131

  Fly   134 LELRFSKRTRQ--LVTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGG 196
            |..||..:..|  |..::.:|..|..:...:|..::..:...|.:|:|...::.:|...||:.||
  Rat   132 LRKRFGGKRIQIYLSVLSLLLYIFTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITGG 196

  Fly   197 IKAVVWTDVVQGSVMLISVVLVAILGTSNTGGITNVLEN--------AAEGG----------RFD 243
            :.||::||.:|.::||:...::........||....::.        .::|.          |.|
  Rat   197 LAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRAD 261

  Fly   244 FSFGI--DPRLRLTFISGMASGLLMWTGKL-GL----------DQSCVQRIVSLPSYGHAKRCLL 295
             ||.|  ||          .:|.:.|.|.: ||          ||..|||.:|..:..|.|....
  Rat   262 -SFHIFRDP----------ITGDMPWPGLIFGLSILALWYWCTDQVIVQRCLSAKNMSHVKAGCT 315

  Fly   296 MAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDK-----------LMPFFIQDIMGHMM 349
            :.|...||.|......|:|....|  .|.|...|.|:..|           ..|..:.::|.:
  Rat   316 LCGYLKLLPMFLMVMPGMISRILY--TDKIACVLPSECKKYCGTPVGCTNIAYPTLVVELMPN-- 376

  Fly   350 GMPGVFISCVFSASLSSLSASLNSFAGVVYFD-YIKPRINHSEAKANATMKLVIVVMGAYCIVGG 413
            |:.|:.:|.:.::.:|||::..||.:.:...| |.|.|...||.:.....:|.|:|:....|...
  Rat   377 GLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKGASEKELMIAGRLFILVLIGISIAWV 441

  Fly   414 FIVQNFNS--IIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLV 465
            .|||:..|  :...:.:||......:..||.|.:|..|.|...|..|:....|:
  Rat   442 PIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPGAFWGLILGFLI 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	116/485 (24%)
Slc5a1	NP_037165.1	SLC5-6-like_sbd	27..665	CDD:444915	116/485 (24%)