Protein Alignment salt and Slc5a11

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001093952.2
• Gene: Slc5a11 / 252854
• RGDID: 621410
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 161/683 - (23%)
• Similarity: 266/683 - (38%)
• Gaps: 161/683 - (23%)

  Fly    29 DYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQL----------SG 83
            |.:|..|.......:|::....:| ::|.:.|...|..|...||..||.:|.:          ||
  Rat    28 DIVVLVLYFLFVLAVGLWSTVRTK-RDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSG 91

  Fly    84 VAM-MSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRF--SKRTRQL 145
            .|: :||.|    :..|.:|       ||.:|.:|.:|::....|:...|||..||  |:....|
  Rat    92 AAVGISVAA----YELNGLF-------SVLMLAWIFLPIYIAGQVTTMPEYLRRRFGGSRIPITL 145

  Fly   146 VTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSV 210
            ..:...:..|..:.|.|:..::...|....:::|....:.::...||:.||:.||::||.:|..:
  Rat   146 AVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAVTALYTVAGGLAAVIYTDALQTVI 210

  Fly   211 MLISVVLVAILGTSNTGGI------------TNVLENAAEGGRFDFSFGI--DPRLRLT------ 255
            |||...::.....:..||:            :|..||::.|...:.:|.|  ||   ||
  Rat   211 MLIGAFILMGYSFAAVGGMEGLKDQYFLALASNRSENSSCGLPREDAFHIFRDP---LTSDLPWP 272

  Fly   256 -FISGMA-SGLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAG---VGFLLIMSFTCFTGIIM 315
             .:.||: ..|..|.    .||..|||.::..:..|||...|||.   |..|.:|.|......|:
  Rat   273 GILFGMSIPSLWYWC----TDQVIVQRSLAAKNLSHAKGGSLMAAYLKVLPLFLMVFPGMVSRIL 333

  Fly   316 FAYYYGC--DPIQAGLVSKP----DKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSF 374
            |.....|  ..|...:.|.|    |...|..:.:::  ..|:.|:.::.:.:|.:|||::..||.
  Rat   334 FPDQVACAHPDICQRVCSNPSGCSDIAYPKLVLELL--PTGLRGLMMAVMVAALMSSLTSIFNSA 396

  Fly   375 AGVVYFD---YIKPRINHSEAK-ANATMKLVIVVMGAYCI------VGG--FI-VQNFNSIIQTM 426
            :.:...|   :|:||.:..|.. ......|.:|::....|      .||  || :|:.:|.:|.
  Rat   397 STIFTMDLWHHIRPRASERELMIVGRVFVLALVLVSILWIPVVQASQGGQLFIYIQSISSYLQP- 460

  Fly   427 WTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQMNFKAGLIKYDPLPNGL 491
                     .|..||.:|.|..|.|.|.|.||:....|:.|..:|...:..:....:.|..|..:
  Rat   461 ---------PVAVVFIMGCFWKRTNEKGAFSGLILGLLLGLVRLILDFVYVQPRCDQPDDRPAVV 516

  Fly   492 DQCEAKGFEVILNAIR-----------------------------------------------NK 509
            .......|.:||::..                                               ::
  Rat   517 KDVHYLYFSMILSSTTLITVFTVSWFTETPSKEMVSRLTWFTRHEPVAQKDSVPPENPLSLTISQ 581

  Fly   510 NVTNVGTTAIPSLEAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEK 574
            |.|...|.....||:.:|.||...|:      ..|....|||.|:|   |...|      :|:::
  Rat   582 NGTTEATGISIQLESVQEATTKAHSD------GVSPKQSKVLKAIL---WLCGM------EKDKE 631

  Fly   575 QNPKLYSPFVRSMLNKPSPVLELEELPL-KTPL 606
            :.|....|.          ::.|||.|| ||.|
  Rat   632 EPPSKVEPV----------IVSLEENPLVKTLL 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	150/640 (23%)
Slc5a11	NP_001093952.2	SLC5-6-like_sbd	28..673	CDD:444915	161/683 (24%)