Protein Alignment salt and Slc5a11

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_666310.1
• Gene: Slc5a11 / 233836
• MGIID: 1919316
• Length: 673
• Species: Mus musculus
• Alignment Length: 650
• Identity: 152/650 - (23%)
• Similarity: 263/650 - (40%)
• Gaps: 154/650 - (23%)

  Fly    30 YIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQL----------SGV 84
            |.:|.|      .:|::....:| ::|.:.|...|..|...||..||.:|.:          ||.
Mouse    35 YFLFVL------AVGLWSTVRTK-RDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGA 92

  Fly    85 AM-MSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRF--SKRTRQLV 146
            |: :||.|    :..|.:|       ||.:|.::.:|::....|:...|||..||  ::.:..|.
Mouse    93 AVGISVAA----YELNGLF-------SVLMLAWVFLPIYIAGQVTTMPEYLRRRFGGNRISITLA 146

  Fly   147 TITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVM 211
            .:...:..|..:.|.|:..::...|....:::|....:.:|...||:.||:.||::||.:|..:|
Mouse   147 VLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITALYTVAGGLAAVIYTDALQTVIM 211

  Fly   212 LISVVLVAILGTSNTGGI------------TNVLENAAEGGRFDFSFGI--DPRLRLT------- 255
            ||...::.....:..||:            :|..||::.|...:.:|.|  ||   ||
Mouse   212 LIGAFILMGYSFAAVGGMEGLKDQYFLALASNRSENSSCGLPREDAFHIFRDP---LTSDLPWPG 273

  Fly   256 FISGMA-SGLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAG---VGFLLIMSFTCFTGIIMF 316
            .:.||: ..|..|.    .||..|||.::..:..|||...|||.   |..|.:|.|......::|
Mouse   274 ILFGMSIPSLWYWC----TDQVIVQRSLAAKNLSHAKGGSLMAAYLKVLPLFLMVFPGMVSRVLF 334

  Fly   317 AYYYGC--DPIQAGLVSKP----DKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFA 375
            .....|  ..|...:.|.|    |...|..:.:::  ..|:.|:.::.:.:|.:|||::..||.:
Mouse   335 PDQVACAHPDICQRVCSNPSGCSDIAYPKLVLELL--PTGLRGLMMAVMVAALMSSLTSIFNSAS 397

  Fly   376 GVVYFD---YIKPRINHSEAKANA---TMKLVIVVMGAYCIV----GG--FI-VQNFNSIIQTMW 427
            .:...|   :|:||.:..|.....   ...||:|.:....||    ||  || :|:.:|.:|.
Mouse   398 TIFTMDLWNHIRPRASERELMIVGRIFVFALVLVSILWIPIVQASQGGQLFIYIQSISSYLQP-- 460

  Fly   428 TITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQMNFKAGLIKYDPLPNGLD 492
                    .|..||.:|.|..|.|.|.|.||:....|:              ||::
Mouse   461 --------PVAMVFIMGCFWKRTNEKGAFSGLILGLLL--------------GLVR--------- 494

  Fly   493 QCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVF 557
                    :||:.:          .|.|..:.|        .:|...:.|..:.::.::.:....
Mouse   495 --------LILDFV----------YAQPRCDQP--------DDRPAVVKDVHYLYFSMILSFTTL 533

  Fly   558 AWAIPMSYVWPLDKEEKQNPKLYSPFVRSMLNKPSPVLELEELPLKTPLSEEQIKEKENGSATEA 622
            ...:.:|  |..:...|:.....:.|.|.     .||.:.:..|.:||||   :...:||: |||
Mouse   534 ITVVTVS--WFTETPSKEMVSRLTWFTRH-----EPVAQKDSAPPETPLS---LTLSQNGT-TEA 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	136/592 (23%)
Slc5a11	NP_666310.1	SLC5-6-like_sbd	28..673	CDD:444915	151/649 (23%)