Protein Alignment salt and Slc5a5

DIOPT Version :10

• Sequence 1: NP_651889.3
• Gene: salt / 43742
• FlyBaseID: FBgn0039872
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_443215.2
• Gene: Slc5a5 / 114613
• RGDID: 69267
• Length: 618
• Species: Rattus norvegicus
• Alignment Length: 623
• Identity: 194/623 - (31%)
• Similarity: 306/623 - (49%)
• Gaps: 66/623 - (10%)

  Fly    25 FSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSV 89
            |...||.||:.||..|.|||::.|.....:.:.:::..||:::..:||.:||.:|.:|.|.::.|
  Rat    12 FGAWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGV 76

  Fly    90 PAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFILNQ 154
            |||...:|...:::....:|:..:..::.:|:||...:::.|:|||||||:..|...|:.:::..
  Rat    77 PAEAARYGLKFLWMCAGQLLNSLLTAFLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVAT 141

  Fly   155 FLMLPVYMFVPSLAFSQVTGYNI--HLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVL 217
            .|...:.::.|:|..:||||.:|  .|::|.:  ||..||.:||:||||||||.|..|||:...:
  Rat   142 MLYTGIVIYAPALILNQVTGLDIWASLLSTGI--ICTLYTTVGGMKAVVWTDVFQVVVMLVGFWV 204

  Fly   218 VAILGTSNTGGITNVLENAAEGGRFD-FSFGIDPRLRLTFISGMASGLLMWTGKLGLDQSCVQRI 281
            :...|....||..|:|..|....|.: ..|..|||.|.||.:.:..|.|:|....|::|:.|||.
  Rat   205 ILARGVILLGGPRNMLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGGTLVWLSMYGVNQAQVQRY 269

  Fly   282 VSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQDIMG 346
            |:..:.|.||..||:..:|..||::.....||:||.||..|||:..|.:|.||:.||..:.||..
  Rat   270 VACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFE 334

  Fly   347 HMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINHSEAKANATMKLVIV------VM 405
            .:.|:||:|::|.:|.:||:.|.|:|:.|.|...|.||||:     ...|..|||.:      :.
  Rat   335 DLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRM-----PGLAPRKLVFISKGLSFIY 394

  Fly   406 GAYC--------IVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFS 462
            |:.|        ::||       .::|..:|:.|:..|.::|.|.|||.:|.||....:||:|..
  Rat   395 GSACLTVAALSSLLGG-------GVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLAAG 452

  Fly   463 CLVMLWIIINGQMNFKAGLIKYDP-------LPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIP 520
            ..|.||:.:        |...|.|       ||.....|  ....|:|......|.:|    .||
  Rat   453 LAVSLWVAV--------GATLYPPGEQTMGVLPTSAAGC--TNDSVLLGPPGATNASN----GIP 503

  Fly   521 SLEAPKELTTAFDSNRDF---SIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYSP 582
            |        :..|:.|..   :.|..|:.:|..||.|........:||:....|.....|.|...
  Rat   504 S--------SGMDTGRPALADTFYAISYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLWW 560

  Fly   583 FVRSMLNKPSP---VLELEELPLKTPLSEEQIKEKENG 617
            .:.......:|   ...|||..:|.|.....:.:|..|
  Rat   561 DLARQTASVAPKEDTATLEESLVKGPEDIPAVTKKPPG 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salt	NP_651889.3	SLC5sbd_NIS-SMVT	28..566	CDD:271383	181/564 (32%)
Slc5a5	NP_443215.2	SLC5sbd_NIS	15..549	CDD:271393	182/569 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	587..618		2/12 (17%)